The Selous Game Reserve is one of the largest faunal reserves of the world, located in the south of Tanzania. It was named after Englishman Sir Frederick Selous, a famous big game hunter and early conservationist, who died at Beho Beho in this territory in 1917 while fighting against the Germans during World War I. Scottish explorer and cartographer Keith Johnston also died at Beho Beho in 1879 while leading a RSGS expedition to the Great Lakes of Africa with Joseph Thomson. The Selous was designated a UNESCO World Heritage Site in 1982 due to the diversity of its wildlife and undisturbed nature.

The reserve covers a total area of 54,600 km² (21,100 sq mi) and has additional buffer zones. Within the reserve no permanent human habitation or permanent structures are permitted. All (human) entry and exit is carefully controlled by the Wildlife Division of the Tanzanian Ministry of Natural Resources and Tourism. Some of the typical animals of the savanna (for example elephants, hippopotami, African Wild Dog, cape buffalo and crocodiles) can be found in this park in larger numbers than in any other African game reserve or national park.

A game reserve is an area of land set aside for maintenance of wildlife for tourism or hunting purposes. Many game reserves are located in Africa. Most are open to the public, and tourists commonly take sightseeing safaris or hunt wild game.

A game reserve is more than just a piece of land or a place to keep wildlife; it is a place where ecosystems are protected and conservation is a key. Indigenous wildlife in its natural habitat makes for an ideal situation as this helps in providing an environment where growth in numbers at a natural rate can occur.

Some game reserves boast more than one ecosystem, sometimes even five, ranging from valley bushveld, savannah grassland and fynbos to riverine forest and acacia woodland; this provides a dramatic improvement on the types of wildlife that are present and the numerous species of birds that thrive on in these environments.

The biggest attraction is the Big Five game (Africa) - rhinoceros, elephant, buffalo, leopard and lion, named so because of the difficulty in hunting them and not their size, which is why the leopard is on the list and the hippopotamus is not.