- published: 07 Nov 2011
- views: 7919
- author: bradpilon
2:46
Amino Acid Supplements
Amino Acids Supplements - Amino Acid Safety and Amino Acid Toxicity Amino Acids are the bu...
published: 07 Nov 2011
author: bradpilon
Amino Acid Supplements
Amino Acid Supplements
Amino Acids Supplements - Amino Acid Safety and Amino Acid Toxicity Amino Acids are the building blocks of protein. They can be broken down into different ca...- published: 07 Nov 2011
- views: 7919
- author: bradpilon
0:16
How to Pronounce Threonine
Learn how to say Threonine correctly with EmmaSaying's "how do you pronounce" free tutoria...
published: 06 May 2013
author: Emma Saying
How to Pronounce Threonine
How to Pronounce Threonine
Learn how to say Threonine correctly with EmmaSaying's "how do you pronounce" free tutorials. Definition of threonine (oxford dictionary): noun [mass noun] B...- published: 06 May 2013
- views: 22
- author: Emma Saying
0:30
Memorize Threonine
Mnemonic for memorizing threonine....
published: 22 Nov 2010
author: StopSocialismUSA
Memorize Threonine
Memorize Threonine
Mnemonic for memorizing threonine.- published: 22 Nov 2010
- views: 633
- author: StopSocialismUSA
10:00
IsoLeucine Ile Threonine Thr Essential Amino Acids 27SEP10
I updated the Amino Acids using the Schroeder Diamonds (the carbon with the significant ch...
published: 02 Oct 2010
author: CosmicRay137
IsoLeucine Ile Threonine Thr Essential Amino Acids 27SEP10
IsoLeucine Ile Threonine Thr Essential Amino Acids 27SEP10
I updated the Amino Acids using the Schroeder Diamonds (the carbon with the significant chemical character that we focus on-the one holding the -R side group...- published: 02 Oct 2010
- views: 164
- author: CosmicRay137
50:40
aminoacid metabolism 2 " glycine,serine,threonine,branched chain aa "
Date : wdnesday 20-2-2013 content : - Glycine -Serine -Threionine -Branched chain aa....
published: 20 Feb 2013
author: forsan2ndyear
aminoacid metabolism 2 " glycine,serine,threonine,branched chain aa "
aminoacid metabolism 2 " glycine,serine,threonine,branched chain aa "
Date : wdnesday 20-2-2013 content : - Glycine -Serine -Threionine -Branched chain aa.- published: 20 Feb 2013
- views: 175
- author: forsan2ndyear
13:50
Amino acid digestibility and concentration of DE and ME in a threonine co-product
Ferdinando Almeida, Ph. D. student in the Stein Monogastric Nutrition Lab, discusses his r...
published: 29 May 2012
author: SteinNutritionLab
Amino acid digestibility and concentration of DE and ME in a threonine co-product
Amino acid digestibility and concentration of DE and ME in a threonine co-product
Ferdinando Almeida, Ph. D. student in the Stein Monogastric Nutrition Lab, discusses his research into amino acid digestibility and concentration of digestib...- published: 29 May 2012
- views: 81
- author: SteinNutritionLab
2:13
Serine-Threonine-Asparganine-Polar-AminoAcids-SchroederDiamonds9SEP11
Serine Threonine Asparganine Chemical structure using the Fun and Colorful 'Schroeder Diam...
published: 08 Sep 2011
author: CosmicRay137
Serine-Threonine-Asparganine-Polar-AminoAcids-SchroederDiamonds9SEP11
Serine-Threonine-Asparganine-Polar-AminoAcids-SchroederDiamonds9SEP11
Serine Threonine Asparganine Chemical structure using the Fun and Colorful 'Schroeder Diamonds'! SO NOTE THAT EVEN I WAS SPELLING ASPRGANINE WRONG!!!! I was ...- published: 08 Sep 2011
- views: 77
- author: CosmicRay137
0:19
Serine-Valine-Threonine-flipped-PeptideChain-SchroederDiamonds
Serine-Valine-Threonine-Correct FLIPPED Peptide Chain Sequences... see how every other ami...
published: 15 Jul 2011
author: CosmicRay137
Serine-Valine-Threonine-flipped-PeptideChain-SchroederDiamonds
Serine-Valine-Threonine-flipped-PeptideChain-SchroederDiamonds
Serine-Valine-Threonine-Correct FLIPPED Peptide Chain Sequences... see how every other amino acid is on the opposite side of the chain? easy to follow with t...- published: 15 Jul 2011
- views: 85
- author: CosmicRay137
3:50
IV-Threonine
Crush by david archuleta starring: camilla bautista diane capule kathleen ching rei-mari t...
published: 05 Sep 2009
author: Kathleen Ching
IV-Threonine
IV-Threonine
Crush by david archuleta starring: camilla bautista diane capule kathleen ching rei-mari torres jiuliano rodriguez.- published: 05 Sep 2009
- views: 185
- author: Kathleen Ching
18:05
ThreOnine "Documentary" Circa 2003.
It's a little rough, disc was not in good shape. hahaha oh the memories though!...
published: 17 Aug 2013
ThreOnine "Documentary" Circa 2003.
ThreOnine "Documentary" Circa 2003.
It's a little rough, disc was not in good shape. hahaha oh the memories though!- published: 17 Aug 2013
- views: 35
3:36
Threonine na NiemenNonStop
Zespół Threonine w składzie: Sebastian Świątek - bas Paweł Kałwak - instrumenty perkusyjne...
published: 26 Dec 2007
author: kawq1313
Threonine na NiemenNonStop
Threonine na NiemenNonStop
Zespół Threonine w składzie: Sebastian Świątek - bas Paweł Kałwak - instrumenty perkusyjne,chórki Piotr Proniuk - klawisze, wokal Eryk Ciemnoczołowski - gitara.- published: 26 Dec 2007
- views: 603
- author: kawq1313
Vimeo results:
31:43
Amino Acids – Visi New Product
http://www.discovervisi.org or email Sandra at discoverVisi@gmail.com
Amino acids play ce...
published: 15 Mar 2013
author: Visi Weight Loss Canada
Amino Acids – Visi New Product
http://www.discovervisi.org or email Sandra at discoverVisi@gmail.com
Amino acids play central roles both as building blocks of proteins and as intermediates in metabolism. Humans can produce 10 of the 20 amino acids. The others must be supplied in the food. Failure to obtain enough of even 1 of the 10 essential amino acids, those that we cannot make, results in degradation of the body's proteins—muscle and so forth—to obtain the one amino acid that is needed. Unlike fat and starch, the human body does not store excess amino acids for later use—the amino acids must be in the food every day.
Essential amino acids
The 10 amino acids that we can produce are alanine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine and tyrosine. Tyrosine is produced from phenylalanine, so if the diet is deficient in phenylalanine, tyrosine will be required as well. The essential amino acids are arginine (required for the young, but not for adults), histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine. These amino acids are required in the diet. Plants, of course, must be able to make all the amino acids. Humans, on the other hand, do not have all the the enzymes required for the biosynthesis of all of the amino acids.
1:13
William Pao, M.D., Ph.D., Vanderbilt-Ingram Cancer Center
William Pao, M.D., Ph.D.
Vanderbilt-Ingram Cancer Center
Dr. Pao is a physician-scienti...
published: 24 May 2013
author: TEAM DRAFT
William Pao, M.D., Ph.D., Vanderbilt-Ingram Cancer Center
William Pao, M.D., Ph.D.
Vanderbilt-Ingram Cancer Center
Dr. Pao is a physician-scientist with a special interest in thoracic oncology. Dr. Pao's research focuses on identification of genes involved in the pathogenesis of lung tumors and stratifying tumors intoclinically relevant molecular subsets. Using information derived fromthese experiments, Dr.
Read more ....
Education
Ph.D. - Yale University, 1998
M.D. - Yale University, 1990
Fellowship - Memorial Sloan-Kettering Cancer Center, 2005
Fellowship - Memorial Sloan-Kettering Cancer Center, 2004
Internship - New York Presbyterian Hospital, 2000
Residency - New York Presbyterian Hospital, 2000
Research Specialty
The Pao Laboratory aims to perform translational research in the area of solid tumor biology, using lung cancer as a paradigm. The overall goal is to develop molecularly-tailored treatments for patients with lung cancer.
Research Description
Lung cancer is the leading cause of cancer-related death in the U.S and worldwide. Most cases arise in former or current smokers, but about 10% of cases also occur in individuals who smoked less than 100 cigarettes in a lifetime (“never smokers”). Lung cancers are currently classified by histopathological techniques as either small-cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC). In North America, adenocarcinoma (a type of NSCLC) is the most frequent type of histological tumor, accounting for 40% of all cases of lung cancer.
New “targeted” epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) like gefitinib (Iressa) and erlotinib (Tarceva) have given us a window of opportunity to elucidate clinically relevant molecular subsets of lung adenocarcinomas. For example, clinical trials have shown that gefitinib has an overall response rate of 10% in American and European populations, and 28% in Japanese patients. Retrospective analyses suggested that gefitinib is most efficacious in “never smokers” with adenocarcinoma histology. Such findings can now be largely accounted for by research from our group and others showing the relatively high incidence of mutations in the gene encoding EGFR in these respective populations and the association of EGFR mutations with increased sensitivity to both gefitinib and erlotinib.
While EGFR mutations are common in tumors from never smokers, mutations in KRAS, which encodes a signaling molecule downstream of EGFR, more commonly occur in individuals with substantial cigarette use. Moreover, EGFR and KRAS mutations appear to be mutually exclusive, suggesting that EGFR and KRAS mutations within lung epithelia are equivalent in their tumorigenic effects. We found that mutations in KRAS are associated with primary resistance to these drugs. This suggests that pre-treatment mutational profiling of both EGFR and KRAS may help guide treatment decisions regarding the use of these agents.
Unfortunately, virtually all patients who initially respond to gefitinib and erlotinib eventually develop acquired resistance. We have shown that tumor cells from patients whose disease progresses after initial responses on therapy with these agents frequently harbor second-site mutations in EGFR. The predominant second mutation substitutes methionine for threonine at position 790 in EGFR, which is predicted to block binding of gefitinib and erlotinib to the ATP-binding pocket of the kinase. Interestingly, the T790M amino acid change is analogous to changes seen in other kinases targeted by a related kinase inhibitor, imatinib (Gleevec), in patients that develop acquired resistance to that drug. Using a genomic approach, we have also recently found that tumor samples from patients with acquired resistance to gefitinib or erlotinib harbor amplification of MET, which encodes another tyrosine kinase. MET amplification appears to occur independently of T790M mutations. Importantly, MET inhibitors are currently being developed in the clinic.
The Pao Laboratory is now focused on the following:
1) Defining further molecular subsets of lung cancers, based primarily upon mutational profiling of the oncogenome in tumor samples.
2) Elucidating other mechanisms of sensitivity and resistance to EGFR inhibitors in lung cancer. For example, we recently showed that in drug-sensitive EGFR mutant lung cancer cells, induction of BIM is essential for apoptosis triggered by
Youtube results:
7:44
Protease - Wiki Article
A protease is any enzyme that conducts proteolysis, that is, begins protein catabolism by ...
published: 23 May 2013
author: wikispeak10
Protease - Wiki Article
Protease - Wiki Article
A protease is any enzyme that conducts proteolysis, that is, begins protein catabolism by hydrolysis of the peptide bonds that link amino acids together in t...- published: 23 May 2013
- views: 194
- author: wikispeak10
8:30
Protein kinase C.mp4
For more information, log on to- http://shomusbiology.weebly.com/ Download the study mater...
published: 06 Dec 2012
author: Suman Bhattacharjee
Protein kinase C.mp4
Protein kinase C.mp4
For more information, log on to- http://shomusbiology.weebly.com/ Download the study materials here- http://shomusbiology.weebly.com/bio-materials.html Prote...- published: 06 Dec 2012
- views: 721
- author: Suman Bhattacharjee
1:56
The Building Blocks of Your Protein
Alanine, and Aspartate Cysteine, Glycine, Glutamate Lysine, Phenylalanine The building blo...
published: 25 Feb 2012
author: lifewithjuan
The Building Blocks of Your Protein
The Building Blocks of Your Protein
Alanine, and Aspartate Cysteine, Glycine, Glutamate Lysine, Phenylalanine The building blocks of your protein Leucine, and Methionine Aspargine and Glutamine...- published: 25 Feb 2012
- views: 214
- author: lifewithjuan
5:00
Drug Resistance
3D version found at: http://www.youtube.com/watch?v=v9zCqxKfbpo Protein kinases are a grou...
published: 13 Jan 2012
author: URIanimation
Drug Resistance
Drug Resistance
3D version found at: http://www.youtube.com/watch?v=v9zCqxKfbpo Protein kinases are a group of enzymes that transfer a phosphate from a molecule, such as the...- published: 13 Jan 2012
- views: 3387
- author: URIanimation