Sera Monastery (Tibetan: སེ་ར་, Wylie: Se-ra; Chinese: 色拉寺; ) is one of the 'great three' Gelukpa university monasteries of Tibet, located 1.25 miles (2.01 km) north of Lhasa. The other two are Ganden Monastery and Drepung Monastery. The origin of the name 'Sera' is attributed to a fact that the site where the monastery was built was surrounded by wild roses (se ra in Tibetan language) in bloom. The original Sera monastery is located in Lhasa, Tibet, about 5 kilometres (3.1 mi) north of the Jokang and is responsible for some 19 hermitages, including four nunneries, which are all located in the foot hills north of Lhasa. The Sera Monastery, as a complex of structures with the Great Assembly Hall and three colleges, was founded in 1419 by Jamchen Chojey of Sakya Yeshe of Zel Gungtang (1355–1435), a disciple of Tsongkhapa.

During the 1959 revolt in Lhasa, Sera monastery suffered severe damage, with its colleges destroyed and hundreds of monks killed. After the Dalai Lama took asylum in India, many of the monks of the Sera Monastery who survived the attack moved to Bylakuppe in Mysore, India. After initial tribulations, they established a parallel Sera Monastery with Sera Me and Sera Je colleges and a Great Assembly Hall on similar lines to the original monastery, with help from the Government of India. There are now 3,000 or more monks living in Sera, India and this community has also spread its missionary activities to several countries by establishing Dharma centres, propagating knowledge of Buddhism.

The Dalai Lama is a high lama in the Gelug or "Yellow Hat" branch of Tibetan Buddhism. The name is a combination of the Sino-Mongolian word далай (dalai) meaning "Ocean" and the Tibetan word བླ་མ་ bla-ma (with a silent "b") meaning "chief, high priest".

In religious terms, the Dalai Lama is believed by his devotees to be the rebirth of a long line of tulkus who are considered to be manifestations of the bodhisattva of compassion, Avalokiteśvara. Traditionally, the Dalai Lama is thought of as the latest reincarnation of a series of spiritual leaders who have chosen to be reborn in order to enlighten others. The Dalai Lama is often thought to be the leader of the Gelug School, but this position belongs officially to the Ganden Tripa, which is a temporary position appointed by the Dalai Lama who, in practice, exerts much influence. The line of Dalai Lamas began as a lineage of spiritual teachers; the 5th Dalai Lama assumed political authority over Tibet.

For certain periods between the 17th century and 1959, the Dalai Lamas sometimes directed the Tibetan government, which administered portions of Tibet from Lhasa. The 14th Dalai Lama remained the head of state for the Central Tibetan Administration ("Tibetan government in exile") until his retirement on March 14, 2011. He has indicated that the institution of the Dalai Lama may be abolished in the future, and also that the next Dalai Lama may be found outside Tibet and may be female. The Chinese government was very quick to reject this and claimed that only it has the authority to select the next Dalai Lama.