The Mustard procedure was developed in 1963 by Dr. William Mustard at the Hospital for Sick Children in Toronto, Canada.

Dr. Mustard, with support from the Heart and Stroke Foundation of Canada, developed the first operation to correct a congenital heart defect that produced “blue babies”. The defect is called transposition of the great vessels. The condition was common and fatal. The defect causes blood from the lungs to flow back to the lungs and blood from the body to flow back to the body. This occurs because the aorta and the pulmonary artery, the two major arteries coming out of the heart, are connected to the wrong chambers. The babies look blue because there is insufficient oxygen circulating in their bodies.^[1]

The Mustard Procedure allows total correction of transposition of the great vessels. The procedure employs a baffle to redirect caval blood flow to the left atrium which then pumps blood to the left ventricle which then pumps the deoxygenated blood to the lungs. In a normal heart, de-oxygenated blood is pumped into the lungs via the right ventricle. Then it is distributed throughout the body via the left ventricle. In the Mustard procedure, blood is pumped to the lungs via the left ventricle and disseminated throughout the body via the right ventricle.^[1]

The Mustard procedure improved an 80% mortality rate in the first year of life to an 80% survival at age 20.

See also[link]

• Congenital heart disease

The Mustard procedure was largely replaced in the late 1980s by the Jatene procedure (arterial switch), in which the native arteries were switched back to normal flow, so that the RV (right ventricle) would be connected to the pulmonary artery and the LV (left ventricle) would be connected to the aorta. This surgery had not been possible prior to 1985 because of difficulty with re-implanting coronary arteries which perfuse the actual heart muscle itself (myocardium).

References[link]

External links[link]

William Thornton Mustard, OC MBE (August 8, 1914 – December 11, 1987) was a Canadian physician and cardiac surgeon. In 1949, he was one of the first to perform open-heart surgery using a mechanical heart pump and biological lung on a dog at the Banting Institute. He developed two operations named for him: the "Mustard operation" in orthopedics used to help hip use in people with polio and the "Mustard cardiovascular procedure" used to help correct heart problems in "blue babies," which has saved thousands of children worldwide.^[1]

Education and training[link]

Born in Clinton, Ontario, the son of Thornton and Pearl (Macdonald) Mustard, Mustard graduated in medicine from the University of Toronto in 1937.^[1] He spent the next year on an internship at Toronto General Hospital and the following year on an internship in surgery at the Hospital for Sick Children. He then took a fellowship at the New York Orthopedic Hospital. In 1940, he returned to Toronto and spent six months training in general surgery, chest diseases, and neurosurgery.^[2]

World War II service[link]

In 1941, he enlisted in the Royal Canadian Army Medical Corps where he first served as a First Lieutenant rising to become a Major. During World War II, he pioneered an operation that helped keep a patient's limb with severe artery damage rather than amputating it. In 1944, he performed an operation on a leg of a soldier^[2] which would later be recognized with being made a Member of the Military Division of the Order of the British Empire.^[3] In 1941, he married Elise Howe. They had seven children.^[2]

Career at Sick Kids[link]

After the war, he returned to Toronto and was chief resident at the Hospital for Sick Children for six months. He spent another year at the New York Orthopedic Hospital before being appointed surgeon at the Hospital for Sick Children in 1947. He spent a month training with Alfred Blalock in Baltimore. In 1957, he was appointed Chief of Cardiovascular Surgery and retired in 1976.^[2]

He died from a massive heart attack in 1987.^[2]

Honours[link]

In 1976, he was made an Officer of the Order of Canada "in recognition of his many achievements in the field of medicine, particularly as a cardiac surgeon of international repute".^[4] In 1975, he was awarded the Gairdner Foundation International Award. In 1995, he was inducted in the Canadian Medical Hall of Fame.

References[link]

External links[link]

• Canadian Medical Hall of Fame citation

William Thornton
Dr. William Thornton, designer of the United States Capitol
Born	(1759-05-20)May 20, 1759 Jost van Dyke, British Virgin Islands
Died	March 28, 1828(1828-03-28) (aged 68)
Nationality	British; American (1788 - )
Alma mater	University of Aberdeen
Known for	United States Capitol

Dr. William Thornton (May 20, 1759 - March 28, 1828) was a British-American physician, inventor, painter and architect who designed the United States Capitol, an authentic polymath. He also served as the first Architect of the Capitol and first Superintendent of the United States Patent Office.

Early life[link]

From an early age William Thornton displayed interest and discernible talent in "the arts of design," to employ an 18th-century term that is particularly useful in assessing his career. Thornton was born on Jost Van Dyke in the British Virgin Islands, West Indies, in a Quaker community at Tortola,^[1] where he was heir to sugar plantations. He was sent to England at age five to be educated.^[1] Thornton was brought up strictly by his father's relations, Quakers and merchants, in and near the ancient castle town of Lancaster, in northern Lancashire, England. There was never any question of his pursuing the fine arts professionally—he was to be trained for a useful life, according to the Quaker ways. Thus, despite the fact that he had a sizeable income, young Thornton was apprenticed for a term of four years (1777–1781), to a practical physician and apothecary in the Furness district of Lancashire (now Cumbria).

The earliest of Thornton's known writings, a journal he began during his apprenticeship, records almost as many entries for drawing and sketching as notes on medical treatments and nostrums. His subjects were most often flora and fauna, but he also did portraits, landscapes, historical scenes, and studies of machinery, such as the Franklin stove, and managed to construct a camera obscura. This pattern continued when he enrolled as a medical student in the University of Edinburgh in 1781. The architecture of Edinburgh, especially that of the New Town that was being built, surely exerted considerable influence. More direct evidence of his interest in architecture is found in the landscapes and sketches of castles he drew while travelling about Scotland, notably in the Highlands, during these years.

In 1783 Thornton went to London to continue his medical studies; characteristically, he also found time to attend lectures at the Royal Academy. The following year he was off to the Continent, carrying a letter of introduction to Benjamin Franklin, written by his mentor and distant cousin Dr. John Coakley Lettsome. He received his medical degree in 1784 at the University of Aberdeen.^[1]

Thornton then spent time in Paris, before returning to Tortola in 1786.^[1] There, he saw his mother for the first time since boyhood, where he came face to face with the source of his income—half interest in a sugar plantation and ownership of some 70 slaves, the possession of which had begun to trouble him.

Eager to achieve fame (and undoubtedly some expiation) in the cause of anti-slavery, he emigrated to the United States of America in the fall of 1786, moving to Philadelphia. His unsuccessful efforts to lead a contingent of free black Americans to join the small British settlement of London blacks at the mouth of the Sierra Leone River in West Africa were looked on favorably by Philadelphia's Quaker establishment. Some leaders of the new republic—notably James Madison, with whom he lodged at Mrs. Mary House's prominent boarding establishment in 1787 and 1788—were cognizant of Thornton's abolitionist activities. In 1788, he became an American citizen. Thornton married Anna Maria Brodeau, daughter of a school teacher, in 1790.^[2]

Architect[link]

United States Capitol[link]

Thornton's original Capitol Building design

This elevation of the Temple Portico of Tudor Place is from a laser scan project conducted by nonprofit CyArk. The circular Temple Portico that extends into the space of the Saloon is a prominent architectural feature of the house, and one of Thornton's trademarks

In 1789, after briefly practicing medicine and pursuing an interest in steamboats, Thornton submitted a design to the architectural competition for the Library Company of Philadelphia's new hall.^[1] His design won but was somewhat departed from during actual construction. Library Hall was described as the first building in the "modern [classical] style" to be erected in the new nation's leading city.

During his visit to Tortola between October 1790 and October 1792, Thornton learned of the design competitions for the U.S. Capitol and the President's House to be erected in the new Federal City on the banks of the Potomac. Because a design for the Capitol had not been chosen, he was allowed to compete upon his return to Philadelphia. Between July and November 1792 the Washington administration examined closely designs submitted by the French émigré architect Etienne Sulpice Hallet and Judge George Turner. Hallet and Turner had been summoned to the Federal City in August 1792 to present their ideas to the Commissioners of the District of Columbia and local landholders. Both were then encouraged to submit revisions of their designs to accommodate new conditions and requirements. At the beginning of November Turner's new designs were rejected.

The U.S. Capitol when first occupied by Congress, 1800

The painter John Trumbull handed in William Thornton's still "unfinished" revised plan of the Capitol building on January 29, 1793, but the president's formal approbation was not recorded until April 2, 1793. Thornton was inspired by east front of the Louvre, as well as the Pantheon for the center portion of the design.^[3] After more drawings were prepared, enthusiastic praise of Thornton's design was echoed by Jefferson: "simple, noble, beautiful, excellently distributed." For his winning design, Thornton received a prize of $500 and a city lot.

The execution of the design was entrusted to the supervision of Étienne Sulpice Hallet and James Hoban. Hallet proceeded to make numerous revisions, including removing the rotunda under which Washington was to be enshrined upon his death. So, on September 12, 1794 the President appointed Thornton one of the three Commissioners of the Federal District in charge of laying out the new federal city and overseeing construction of the first government buildings, including the Capitol of which he became supervisor and remained in charge until 1802. Despite important changes and additions, especially by Latrobe and Bulfinch, much of the design of the facade of the central portion of the Capitol is his.

Other works[link]

The Octagon House (1800), Washington, DC

Woodlawn Plantation, Fairfax County, Virginia (1805)

Tudor Place (c.1808), Georgetown, Washington, DC

Library Company of Philadelphia (recreated 1954), now Library Hall, American Philosophical Society.

As a consequence of winning the Capitol competition, Thornton was frequently asked to give ideas for public and residential buildings in the Federal City. He responded with designs on several occasions during his tenure as a commissioner, less so after 1802 when he took on the superintendency of the Patent Office.

It was during this time he was asked to design a mansion for Colonel John Tayloe. The Tayloe House, also known as The Octagon House, in Washington, D.C., was erected between 1799 and 1800. It served as a temporary "Executive Mansion" after the 1814 burning of the White House by the British and the house's study was where President Madison signed the Treaty of Ghent ending the War of 1812. In 1899 the building was acquired by the American Institute of Architects, whose national headquarters now nestles behind it.

Around 1800, he designed Woodlawn for Major Lawrence Lewis (nephew of George Washington) and his wife, Eleanor (Nelly) Parke Custis (granddaughter of Martha Washington), on 2,000 acres (8.1 km²) of Mount Vernon land. Sometime around 1808, he designed Tudor Place for Thomas Peter and his wife, Martha Parke Custis (another granddaughter of Martha Washington).

National Register[link]

Many buildings designed by Thornton have been added to the National Register of Historic Places including:

• Library Company of Philadelphia, 5th & Chestnut Sts., Philadelphia, PA; 1789 (demolished 1887; recreated as Library Hall, American Philosophical Society, 1954)
• United States Capitol, Washington, DC; 1793 - exempt
• Prospect Hill, NE of Long Green on Kanes Road, Baltimore, MD; 1796-1798 - added to registry in 1973
• Octagon House, 1741 New York Avenue, NW, Washington, DC; 1799 - added in 1966
• Woodlawn, W of jct. of U.S. 1 and Rte. 235, Fairfax, VA, 1800-05 - added in 1970
• Tudor Place, 1644 31st Street, NW, Washington, DC; 1816 - added in 1966

Superintendent of the Patent Office[link]

Upon the abolition of the board in 1802, President Jefferson appointed Thornton the first Superintendent of the Patent Office. When Washington was burned by the British in 1814, Thornton convinced them not to burn the Patent Office because of its importance to mankind. He held the position from June 1, 1802 until his death in 1828 in Washington, DC. During his tenure, he introduced innovations including the patent reissue practice, which survives to this day.^[4]

Societies[link]

During the 1820s, Thornton was a member of the prestigious society, Columbian Institute for the Promotion of Arts and Sciences, who counted among their members former presidents Andrew Jackson and John Quincy Adams and many prominent men of the day, including well-known representatives of the military, government service, medical and other professions.^[5]

Later life[link]

Thornton was buried in Congressional Cemetery on Capitol Hill.

References[link]

Notes[link]

• Frary, Ihna Thayer (1969). They Built the Capitol. Ayer Publishing. ISBN 0-8369-5089-5. 

Further reading[link]

• Bordewich, Fergus M., "A Capitol Vision From a Self-Taught Architect", Smithsonian magazine, December 2008

External links[link]

• Thornton's designs of the U.S. Capitol
• Tudor Place
• Thornton's grave
• Biography of Thornton on Wikimedia Commons