Oprah Winfrey’s endorsement of Barack Obama was one of the most widely covered and studied developments of the 2008 presidential campaign. Winfrey has been described as the most influential woman in the world for her impact on the culture and her proven record as a taste-maker and trend-setter, and there was much interest in whether that influence could translate politically since she had never before endorsed a candidate. Winfrey first endorsed Obama in September 2006 before he had even declared himself a candidate. In May 2007 Winfrey made her first endorsement of candidate Obama, and in December 2007, she made her first campaign appearances for him. Two economists estimate that Winfrey’s endorsement was worth over a million votes in the Democratic primary race and that without it, Obama would have lost the nomination. Then-Governor of Illinois Rod Blagojevich claimed that the endorsement was so significant in electing Obama president that he considered offering Obama's former seat in the Senate to Winfrey.

Oprah Winfrey (born Orpah Gail Winfrey; January 29, 1954) is an American media proprietor, talk show host, actress, producer, and philanthropist. Winfrey is best known for her self-titled, multi-award-winning talk show, which has become the highest-rated program of its kind in history and was nationally syndicated from 1986 to 2011. She has been ranked the richest African-American of the 20th century, the greatest black philanthropist in American history, and was for a time the world's only black billionaire. She is also, according to some assessments, the most influential woman in the world.

Winfrey was born into poverty in rural Mississippi to a teenage single mother and later raised in an inner-city Milwaukee neighborhood. She experienced considerable hardship during her childhood, claiming to be raped at age nine and becoming pregnant at 14; her son died in infancy. Sent to live with the man she calls her father, a barber in Tennessee, Winfrey landed a job in radio while still in high school and began co-anchoring the local evening news at the age of 19. Her emotional ad-lib delivery eventually got her transferred to the daytime-talk-show arena, and after boosting a third-rated local Chicago talk show to first place, she launched her own production company and became internationally syndicated.

Barack Hussein Obama II (ⁱ/bəˈrɑːk huːˈseɪn oʊˈbɑːmə/; born August 4, 1961) is the 44th and current President of the United States. He is the first African American to hold the office. In January 2005, Obama was sworn in as a U.S. Senator in the state of Illinois. He would hold this office until November 2008, when he resigned following his victory in the 2008 presidential election.

Born in Honolulu, Hawaii, Obama is a graduate of Columbia University and Harvard Law School, where he was the president of the Harvard Law Review. He was a community organizer in Chicago before earning his law degree. He worked as a civil rights attorney in Chicago and taught constitutional law at the University of Chicago Law School from 1992 to 2004. He served three terms representing the 13th District in the Illinois Senate from 1997 to 2004.

Following an unsuccessful bid against the Democratic incumbent for a seat in the United States House of Representatives in 2000, Obama ran for the United States Senate in 2004. Several events brought him to national attention during the campaign, including his victory in the March 2004 Illinois Democratic primary for the Senate election and his keynote address at the Democratic National Convention in July 2004. He won election to the U.S. Senate in Illinois in November 2004. His presidential campaign began in February 2007, and after a close campaign in the 2008 Democratic Party presidential primaries against Hillary Rodham Clinton, he won his party's nomination. In the 2008 presidential election, he defeated Republican nominee John McCain, and was inaugurated as president on January 20, 2009. Nine months later, Obama was named the 2009 Nobel Peace Prize laureate. In April 2011, he announced that he would be running for re-election in 2012.

Larry King (born November 19, 1933) is an American television and radio host whose work has been recognized with awards including two Peabodys and ten Cable ACE Awards. He began as a local Florida journalist and radio interviewer in the 1950s and 1960s and became prominent as an all-night national radio broadcaster starting in 1978. From 1985-2010, he hosted the nightly interview TV program Larry King Live on CNN.

King was born Lawrence Harvey Zeiger in Brooklyn, New York City, to an Austrian immigrant Edward Zeiger, a restaurant owner and defense plant worker, and his wife Jennie Gitlitz, a garment worker, who emigrated from Belarus. King grew up in a religiously observant Jewish home, but in adulthood became an agnostic.

King's father died at 44 of heart disease, and his mother had to go on welfare to support her two sons. His father's death greatly affected King, and he lost interest in school. After graduating from high school, he worked to help support his mother. From an early age, however, he had wanted to go into radio. King is a fan of the Los Angeles Dodgers.

Michelle LaVaughn Robinson Obama (born January 17, 1964) is the wife of the 44th and incumbent President of the United States, Barack Obama, and is the first African-American First Lady of the United States. Raised on the South Side of Chicago, Obama attended Princeton University and Harvard Law School before returning to Chicago and to work at the law firm Sidley Austin, where she met her future husband. Subsequently, she worked as part of the staff of Chicago mayor Richard M. Daley, and for the University of Chicago Medical Center.

Throughout 2007 and 2008, she helped campaign for her husband's presidential bid and delivered a keynote address at the 2008 Democratic National Convention. She is the mother of two daughters, Malia and Sasha, and is the sister of Craig Robinson, men's basketball coach at Oregon State University. As the wife of a Senator, and later the First Lady, she has become a fashion icon and role model for women, and an advocate for poverty awareness, nutrition and healthy eating.