LY-379,268
LY-379,268 is a drug that is used in neuroscience research, which acts as a potent and selective agonist for the group II metabotropic glutamate receptors (mGluR2/3).
It is derived from the older mGluR group II agonist eglumegad, and led on to the development of the more potent compound LY-404,039, but is still widely used in research itself. LY-379,268 has sedative, neuroprotective, anti-addictive and anticonvulsant effects in animals, and blocks the effects of PCP and DOI, which has led to research into LY-379,268 and similar compounds as antipsychotic drugs for the treatment of schizophrenia in animals.
There are inconsistent findings about an additional activity as a dopamine D2 receptor partial agonist.
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References
Podcasts:
Leave Wit You (I Think I Wanna)
[intro:]
uh-huh, uh-huh
uh-huh, uh-huh
[verse 1:]
lookin' familiar, i don't know,
have i seen you somewhere before,
kill the small talk let's hit the floor, (are you ready)
to do something you aint done before,
i'll work it 'til you can't take no more,
i think i'm the girl you came here for, (if you can't get it)
[hook:]
i like it
what your doin'
how your movin'
so keep it comin' boy put it on me
[chorus:]
i think i wanna leave wit you do you wanna leave wit me
tell me what you wanna do boy
oh-oh-oh
i think i wanna leave wit you do you wanna leave wit me tell me what you wanna do boy
(if you can't get it)
[verse 2:]
you're lookin' at me like you want more, so after the party let's explode, turn off the lights
and lock the door, (when we're ready) but we aint leavin' here 'til i'm full, freakin' eachother
'til we sore, think i'm the girl you came here for (if you can't get it)
[hook]
[chorus]