ABT-724 is a drug which acts as a dopamine agonist, and is selective for the D4 subtype. It was developed as a possible drug for the treatment of erectile dysfunction, although poor oral bioavailability means alternative drugs such as ABT-670 may be more likely to be developed commercially. Nonetheless, it continues to be used in scientific research into the function of the D4 receptor.
Franz Wilhelm Abt (22 December 1819 – 31 March 1885) was a German composer and choral conductor. He composed roughly 3,000 individual works mostly in the area of vocal music. Several of his songs were at one time universally sung, and have obtained a more or less permanent place in the popular repertory. During his lifetime, Abt was a renowned choral conductor and he spent much of the last three decades of his life working as a guest conductor with choirs throughout Europe and in the United States.
Abt was born at Eilenburg in Prussian Saxony, and showed musical talent at an early age. His father was a clergyman and a talented pianist, and it is he who gave Franz his earliest instruction in music. Like his father, Abt was interested in both music and theology, and he followed both pursuits at the Thomasschule Leipzig and the University of Leipzig with the ultimate intention of becoming a member of the clergy. While in school, Abt became friends with Albert Lortzing, Felix Mendelssohn, and Robert Schumann.
Roger Dean Miller, Jr. (born October 15, 1965, in Los Angeles, California) is an American country music artist, known professionally as Dean Miller. He is the son of Roger Miller, a country pop artist who had several hit singles between the 1960s and 1980s. Dean Miller has recorded three studio albums (one of which was not released), in addition to charting four singles on the Hot Country Songs charts and writing singles for Trace Adkins and Terri Clark. His highest-peaking single was "Nowhere, USA", which reached #54 in 1997.
Although born in Los Angeles, Dean Miller was raised in Santa Fe, New Mexico. He got his musical start in local clubs around Santa Fe, before moving back to Los Angeles in the early 1980s and joining a band called the Sarcastic Hillbillies. At the same time, he attended college, in addition to briefly pursuing a career in acting. Miller later moved to Nashville, Tennessee, where he worked as a staff songwriter for Sony/Tree Publishing.
By 1995, he was signed to the Nashville division of Liberty Records (which was later assumed into Capitol Records Nashville). Two years later, his eponymous debut album was released on the Capitol label. The lead-off single "Nowhere, USA" received significant airplay in Chicago even before its release date; however, it and two additional singles failed to reach Top 40 on the Billboard Hot Country Singles & Tracks (now Hot Country Songs) charts. Another single, "Wake Up and Smell the Whiskey", was co-written and previously recorded by Brett James, who would later become a popular Nashville songwriter in the 2000s. In addition, the album sold poorly, and Miller was dropped from the Capitol roster not long afterward. In 2000, two country artists charted with singles that Miller co-wrote: Terri Clark's "A Little Gasoline", which was a Top Ten Hit and Trace Adkins's "I'm Gonna Love You Anyway".
Misty Copeland (born September 10, 1982) is an American ballet dancer, described by many accounts as the first African American female soloist for the American Ballet Theatre (ABT), one of the three leading classical ballet companies in the United States (along with New York City Ballet and San Francisco Ballet). However, Anne Benna Sims and Nora Kimball, who were with the ABT in the early and mid 1980s respectively, preceded her. In this role as the third African-American soloist and first in two decades with ABT, she has endured the cultural pressure associated with it.
Copeland is considered a prodigy who rose to stardom despite not starting ballet until the age of 13. By age 15, Copeland's mother and ballet teachers, who were serving as her custodial guardians, fought a custody battle over her. Meanwhile, Copeland, who was already an award-winning dancer, was fielding professional offers. The 1998 legal proceedings involved filings for emancipation by Copeland and restraining orders by her mother. Both sides dropped legal proceedings, and Copeland moved home to begin studying under a new teacher who was a former ABT member.