Benzoctamine

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Benzoctamine
Systematic (IUPAC) name
N-methyl-9,10-ethanoanthracene-9(10H)-methanamine
Clinical data
Pregnancy cat.  ?
Legal status  ?
Routes Intravenous, oral
Pharmacokinetic data
Metabolism Hepatic
Half-life 2 to 3 hours
Excretion Renal
Identifiers
CAS number 17243-09-9 YesY
ATC code N05BD01
PubChem CID 28425
ChemSpider 26444 YesY
UNII 734MM7Y191 YesY
Chemical data
Formula C18H19N 
Mol. mass 249.35 g/mol
 YesY (what is this?)  (verify)

Benzoctamine is a drug that possesses sedative and anxiolytic properties. It is different from most sedative drugs because in most clinical trials it does not produce respiratory depression, but actually stimulates the respiratory system. When co-administered with other drugs that cause respiratory depression, like morphine, it can cause increased respiratory depression. Peak effects are reached at about an hour, and effects wear off after about 2–3 hours. This drug is also used as a sedative in the hospital scene in patients who have respiratory failure.

It appears to reduce turnover of serotonin.[1]

Its effects can be variable.[2]

See also [edit]

References [edit]

  1. ^ Lippmann W, Pugsley TA (August 1974). "Effects of benzoctamine and chlordiazepoxide on turnover and uptake of 5-hydroxytryptamine in the brain". Br. J. Pharmacol. 51 (4): 571–5. PMC 1778070. PMID 4480288. 
  2. ^ BENZOCTAMINE-A STUDY OF THE RESPIRATORY EFFECTS OF ORAL DOSES IN HUMAN VOLUNTEERS AND INTERACTIONS WITH MORPHINE IN MICE - UTTING and PLEUVRY 47 (9): 987 - British Journal of Anaesthesia