MPPF
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MPPF | |
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4-Fluoro-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridyl)benzamide |
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Identifiers | |
CAS number | 155204-26-5 |
PubChem | 6603915 |
Jmol-3D images | Image 1 |
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Properties | |
Molecular formula | C25H27FN4O2 |
Molar mass | 434.51 g/mol |
(verify) (what is: / ?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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Infobox references |
MPPF, with the full name 2'-methoxyphenyl-(N-2'-pyridinyl)-p-fluoro-benzamidoethyipiperazine, is a compound that binds to the serotonin-1A receptor. Labeled with fluorine-18 it has been used as a radioligand with positron emission tomography.[1] It has, e.g., been used to examine the difference in neuroreceptor binding in the human brain across sex and age.[2]
See also [edit]
References [edit]
- ^ D. Le Bars (May 1998). "High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-18FMPPF, a Fluoro Analog of WAY-100635". Nuclear Medicine and Biology 25 (4): 343–350. doi:10.1016/S0969-8051(97)00229-1.
- ^ Nicolas Costes; Merlet, I; Ostrowsky, K; Faillenot, I; Lavenne, F; Zimmer, L; Ryvlin, P; Le Bars, D (December 2005). "A18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging". the Journal of Nuclear Medicine 46 (12): 1980–1989. PMID 16330560.
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