Thiethylperazine
From Wikipedia, the free encyclopedia
Systematic (IUPAC) name | |
---|---|
2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine | |
Clinical data | |
AHFS/Drugs.com | Micromedex Detailed Consumer Information |
Pregnancy cat. | ? |
Legal status | ? |
Pharmacokinetic data | |
Protein binding | 60% |
Identifiers | |
CAS number | 1420-55-9 |
ATC code | R06AD03 |
PubChem | CID 5440 |
DrugBank | DB00372 |
ChemSpider | 5245 |
UNII | 8ETK1WAF6R |
KEGG | D02354 |
ChEBI | CHEBI:9544 |
ChEMBL | CHEMBL1378 |
Chemical data | |
Formula | C22H29N3S2 |
Mol. mass | 399.618 g/mol |
|
|
|
|
(what is this?) (verify) |
Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.
Thiethylperazine activates the transport protein ABCC1 that clears beta-amyloid from brains of mice. [1]
[edit] References
- ^ Science Daily (September 1, 2011). "Alzheimer Disease: Transport Protein ABCC1 Plays Key Role in Clearing Beta-Amyloid from Brains of Mice.". Retrieved September 1, 2011.
Bourquin, J. P.; Schwarb, G.; Gamboni, G.; Rischer, R.; Ruesch, L.; Uldimann, S. G.; Theuss, U.; Schenke, E.; Renz, J.; Helv. Chim. Acta 1958, 41, 1072.
|
|
|
|
This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it. |
This drug article relating to the respiratory system is a stub. You can help Wikipedia by expanding it. |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |