Thiazepine

1,3-thiazepine

1,4-thiazepine

Diltiazem. 1,4-thiazepine is the seven membered ring in the middle.

Thiazepines are a substituted thiepins, with a nitrogen replacing a carbon in the seven-membered heterocyclic compound.

Types include:

• 1,3-thiazepine
• 1,4-thiazepine

Benzothiazepines (such as diltiazem) have a single benzene attached to the ring, while dibenzothiazepines have two.

• Diltiazem, a benzothiazepine, is intermediate in properties between verapamil and the dihydropyridines.
• Diltiazem is used to treat variant angina (Prinzmetal's angina), either naturally occurring or drug-induced and stable angina.

External links

• Thiazepines at the US National Library of Medicine Medical Subject Headings (MeSH)