Org 21465
From Wikipedia, the free encyclopedia
![]() |
|
---|---|
Systematic (IUPAC) name | |
[2-[(2S,3S,5S,8S,9S,10S,13S,14S,17S)-2-(2,2-dimethylmorpholin-4-yl)-3-hydroxy-10,13-dimethyl-11-oxo-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl]methanesulfonate | |
Clinical data | |
Pregnancy cat. | ? |
Legal status | ? |
Identifiers | |
ATC code | ? |
PubChem | CID 10697702 |
Chemical data | |
Formula | C27H43NO7S |
Mol. mass | 525.696 |
|
|
![]() |
Org 21465 is a synthetic neuroactive steroid, with sedative effects resulting from its action as a GABAA receptor positive modulator. It is similar to related drugs such as Org 20599, and was similarly developed as an improved alternative to other sedative steroids such as althesin and allopregnanolone, which despite its superior properties in some respects has not proved to offer enough advantages to be accepted into clinical use.[1][2]
See also [edit]
References [edit]
- ^ Sear JW. ORG 21465, a new water-soluble steroid hypnotic: more of the same or something different? British Journal of Anaesthsia. 1997 Oct;79(4):417-9. PMID 9389254
- ^ Vanlersberghe C, Camu F. Etomidate and other non-barbiturates. Handbook of Experimental Pharmacology. 2008;(182):267-82. PMID 18175096
![]() |
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it. |