Divaplon

Divaplon
Systematic (IUPAC) name
	(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone
Clinical data
Pregnancy cat.	?
Legal status	?
Identifiers
CAS number	90808-12-1
ATC code	None
PubChem	CID 65822
UNII	4AOV43246G
Chemical data
Formula	C17H17N3O2
Mol. mass	295.336
	SMILES CCC1=C(N2C=C(N=C2N=C1OC)C(=O)C3=CC=CC=C3)C;
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Divaplon (RU-32698) is a nonbenzodiazepine, anxiolytic and anticonvulsant drug from the pyrazolopyrimidine family of drugs. It acts as a partial agonist at the "benzodiazepine site" of the GABA_A receptor in the brain.^[1]^[2]^[3]

References [edit]

^ Feely, M; Boyland, P; Picardo, A; Cox, A; Gent, JP (1989). "Lack of anticonvulsant tolerance with RU 32698 and Ro 17-1812". European Journal of Pharmacology 164 (2): 377–80. doi:10.1016/0014-2999(89)90482-2. PMID 2759183.
^ Sanger, DJ; Joly, D; Perrault, G (1995). "Benzodiazepine (omega) receptor partial agonists and the acquisition of conditioned fear in mice". Psychopharmacology 121 (1): 104–8. doi:10.1007/BF02245596. PMID 8539334.
^ Pellón, R; Ruíz, A; Lamas, E; Rodríguez, C (2007). "Pharmacological analysis of the effects of benzodiazepines on punished schedule-induced polydipsia in rats". Behavioural Pharmacology 18 (1): 81–7. doi:10.1097/FBP.0b013e3280143212. PMID 17218801.