Butaclamol
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| Systematic (IUPAC) name | |
| 3-(1,1-dimethylethyl)-2,3,4,4a,8,9, 13b,14-octahydro-1H-benzo[6,7]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-ol | |
| Clinical data | |
| Pregnancy cat. | ? |
| Legal status | ? |
| Identifiers | |
| CAS number | 36504-93-5 |
| ATC code | None |
| PubChem | CID 37459 |
| IUPHAR ligand | 62 |
| ChemSpider | 34364 |
| UNII | A7A2802VNL  |
| ChEMBL | CHEMBL479587 |
| Chemical data | |
| Formula | C25H31NO |
| Mol. mass | 361.52 g/mol |
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Butaclamol (AY-23,028) is an antipsychotic which was never marketed.[1] Sold as the hydrochloride salt for use in research, the compound acts as a dopamine receptor antagonist. [2]
[edit] Chemistry
pKa = 7.15 (uncorrected for ionic strength)[3]
[edit] See also
[edit] References
- ^ Dictionary of organic compounds - Google Books.
- ^ http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5=SEARCH_CONCAT_PNO%7CBRAND_KEY&N4=D033%7CSIGMA&N25=0&QS=ON&F=SPEC
- ^ F. A. Chrzanowski, B. A. McGrogan, B. E. Maryanoff (1985). "The pKa of butaclamol and the mode of butaclamol binding to central dopamine receptors." J. Med. Chem. 28 399-400.
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