Conan Christopher O'Brien (born April 18, 1963) is an American television host, comedian, writer, producer and performer. Since November 2010 he has hosted Conan, a late-night talk show that airs on the American cable television station TBS.

O'Brien was born in Brookline, Massachusetts, and raised in an Irish Catholic family. He served as president of the Harvard Lampoon while attending Harvard University, and was a writer for the sketch comedy series Not Necessarily the News. After writing for several comedy shows in Los Angeles, he joined the writing staff of Saturday Night Live, and later of The Simpsons. He hosted Late Night with Conan O'Brien from 1993 to 2009, followed by seven months hosting The Tonight Show with Conan O'Brien, the only person to serve as the permanent host for both NBC programs.

O'Brien was born in Brookline, Massachusetts (a suburb of Boston) to Thomas O'Brien, a physician, epidemiologist, and professor of medicine at Harvard, and Ruth O'Brien (née Reardon), an attorney and partner at the Boston firm Ropes & Gray. He is the third of six children. O'Brien's family is Irish Catholic and descends from pre-Civil War era immigrants. In a Late Night episode, O'Brien paid a visit to County Kerry, Ireland, where his ancestors originated.