The River Tyne ⁱ/ˈtaɪn/ is a river in North East England. It is formed by the confluence of two rivers: the North Tyne and the South Tyne. These two rivers converge at Warden Rock near Hexham in Northumberland at a place dubbed 'The Meeting of the Waters'.

The North Tyne rises on the Scottish border, north of Kielder Water. It flows through Kielder Forest, and passes through the village of Bellingham before reaching Hexham.

The South Tyne rises on Alston Moor, Cumbria and flows through the towns of Haltwhistle and Haydon Bridge, in a valley often called the Tyne Gap. Hadrian's Wall lies to the north of the Tyne Gap. Coincidentally the source of the South Tyne is very close to the sources of the other two great rivers of the industrial north east namely the Tees and the Wear. The South Tyne Valley falls within the North Pennines Area of Outstanding Natural Beauty (AONB) - the second largest of the 40 AONBs in England and Wales.

The combined Tyne flows from Hexham, the area where the river's now thriving barbel stocks were first introduced in the mid 1980s, through Corbridge in Northumberland. It enters the county of Tyne and Wear between Clara Vale (in the Borough of Gateshead on the south bank) and Tyne Riverside Country Park (in Newcastle upon Tyne on the north bank) and continues to divide Newcastle and Gateshead for 13 miles (21 km), in the course of which it is spanned by 10 bridges. To the east of Gateshead and Newcastle, the Tyne divides Hebburn and Jarrow on the south bank from Walker and Wallsend on the north bank. Jarrow and Wallsend are linked underneath the river by the Tyne Tunnel. Finally it flows between South Shields and North Shields into the North Sea. As it passes through the Tyneside conurbation, the river marks the historic border between County Durham (to the south) and Northumberland (to the north).