Elvin A. Kabat

Elvin Abraham Kabat (September 1, 1914 – June 16, 2000) was an American biomedical scientist and one of the founding fathers of modern quantitative immunochemistry. In 1977, Kabat was awarded the Louisa Gross Horwitz Prize from Columbia University in 1977 and the National Medal of Science in 1991. He is the father of Jon Kabat-Zinn, the founding director of the Stress Reduction Clinic and the Center for Mindfulness in Medicine, Health Care, and Society at the University of Massachusetts Medical School. He was the president of the American Association of Immunologists from 1965 to 1966, a member of the National Academy of Sciences and a fellow of the American Academy of Arts and Sciences.

Work

Kabat was instrumental in the discovery of the structural and genetic basis for the remarkable specificity of antibodies. Kabat first demonstrated that antibodies are gamma globulins. He characterized the size and stunning heterogeneity of antibody-combining sites. Kabat and his coworkers determined the structures of the major blood group antigens, the embryonic-stage-specific carbohydrate antigens and the carbohydrate markers of leukocyte (white blood cell).