The history of tetracyclines, including the rise of Lederle-Cyanamid's Aureomycin and Pfizer's Terramycin. ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🔗 L I N K S 🔗 📱Instagram: https://www.instagram.com/patkellyteaches/ 🐦Twitter: https://twitter.com/PatKellyTeaches 💰Patreon: https://www.patreon.com/corporis 🔬Main channel: www.youtube.com/corporis/ 📚My favorite books https://docs.google.com/document/d/1wuG-8EiF2lMbFdEG-9k1qi1d1KZAdGK1o41o7SYed_k/edit?usp=sharing 🔑 P A T R O N S 🔑 Joanne K Sal F. Jim Clay Jr Ansel K Brandon K Pranav M Paul Brendan P Dane M Kristoffer R Jakub V Joe B Karly N Mindi F Drake W Kathy K Mike W Hyeon-Seo Jacob S. Robin B Robb W Sarah B Dontae W Karen S Michael R Brian H Jonathan G Brian T Waffles the Dog Thelma S Silverstar Brian B Michael G Zoe C SOURCES The Miracle Cure by William Rosen https://www.amazon.com/Miracle-Cure-Creation-Antibiotics-Medicine/dp/0525428100?&_encoding=UTF8&tag;=corporis-20&linkCode;=ur2&linkId;=8c4b80078cd36c6e3dd313b4c3db2694&camp;=1789&creative;=9325 Actinomycetes: A Never-Ending Source of Bioactive Compounds—An Overview on Antibiotics Production (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8143475/ Tetracycline antibiotics (2021) https://link.springer.com/content/pdf/10.1007/s40828-021-00138-x.pdf Tetracycline, StatePearls (updated 2023) https://www.ncbi.nlm.nih.gov/books/NBK549905/ Antibiotic Discovery and Development (2012) http://cmdr.ubc.ca/bobh/wp-content/uploads/2017/01/BC-Schurek-2012.pdf The Development of Third-Generation Tetracycline Antibiotics and New Perspectives (2021) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8707899/ PIONEER LEADERS IN PLANT PATHOLOGY: BENJAMIN MINGE DUGGAR (1982) https://www.annualreviews.org/doi/pdf/10.1146/annurev.py.20.090182.000341 Dr. Benjamin Duggar Dies at 84 (1956) https://timesmachine.nytimes.com/timesmachine/1956/09/11/84708966.html?pageNumber=35 AUREOMYCIN: A PRODUCT OF THE CONTINUING SEARCH FOR NEW ANTIBIOTICS by Duggar (1948) https://nyaspubs.onlinelibrary.wiley.com/doi/abs/10.1111/j.1749-6632.2011.06254.x?casa_token=6iXyYOyDzDsAAAAA%3APTYWGc8C_sEfntboUBguIIShANSarGUeJAAjbREghxW-vlY9OxCeY2ef9PvZ2jh3g656aFwMXidmgCBf Aureomycin, a New Antibiotic (1949) https://www.nature.com/articles/163159a0.pdf Chloramphenicol fact sheet from Pfizer https://labeling.pfizer.com/ShowLabeling.aspx?id=14816 Public Policy: Antitrust & Antibiotics (1961) https://web.archive.org/web/20110205040226/http://www.time.com/time/magazine/article/0,9171,895666,00.html U.S. vs Pfizer (1974) https://www.justice.gov/media/1235821/dl?inline Tetracycline litigation https://en.wikipedia.org/wiki/Tetracycline_litigation Casetext US vs Pfizer (1982) https://casetext.com/case/in-re-coordinated-pretrial-proceedings-etc-9 An annotated version of the script with sources in footnotes can be found here: https://www.patreon.com/posts/tetracyclines-of-93954403 IMAGES Wellcome polio vaccine. Wellcome Collection. Source: Wellcome Collection. Licence: Attribution 4.0 International (CC BY 4.0) https://wellcomecollection.org/works/qps38n3k/images?id=vrbvbens View of Sanborn Field from the adjacent Bond Life Sciences Center on the University of Missouri campus by Lwtwb8 (CC BY-SA 3.0) https://en.wikipedia.org/wiki/Sanborn_Field#/media/File:SanbornField.png https://www.flickr.com/photos/boston_public_library/4899342506/in/photostream/ Rickettsia typhi by David H. Walker (UTMB), George Weinstock (BCM-HGSC) https://www.hgsc.bcm.edu/rickettsia-typhi Tetracycline HCl substance by Rillke Creative Commons Attribution-Share Alike 3.0 Unported https://commons.wikimedia.org/wiki/File:Tetracycline-HCl_substance_photo.jpg Streptomyces rimosus, Leibniz-Institut DSMZ. Creative Commons Attribution 4.0 International License. (CC-BY 4.0) https://bacdive.dsmz.de/strain/15515 Arthur M Sackler in his office. Smithsonian's Freer and Sackler Galleries. CC BY-SA 2.0 DEED https://en.wikipedia.org/wiki/Arthur_M._Sackler#/media/File:Arthur_M._Sackler.jpg Parke, Davis and Company, manufacturing chemists, Detroit, Michigan. Packaging pills in the finishing department https://www.loc.gov/resource/ds.14946/ Antimicrobial sensitivity testing of Staphylococcus aureus on MHA after over night incubation by Ajay Kumar Chaurasiya CC BY-SA 4.0 DEED https://commons.wikimedia.org/wiki/File:Antibiogram_of_Staphylococcus_aureus_on_MHA.jpg VIDEOS The antibiotics and terramycin https://wellcomecollection.org/works/m2raqspe Age of Promise (1956) https://wellcomecollection.org/works/jkhgxzzj ⌛T I M E S T A M P S ⌛ 0:00 Intro 0:46 Part 1: Pay Dirt 6:52 Part 2: From the Earth 12:20 The Lawsuit 14:52 Part 3: New Generations of Tetracyclines 💻 C O N T A C T 💻 If you’d like to sponsor a video or have other business inquiries: patkellyteaches [at] gmail.com

• published: 03 Dec 2023
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