638 Ways to Kill Castro is a Channel 4 documentary film, broadcast in the United Kingdom on November 28, 2006, which tells the story of some of the numerous attempts of the Central Intelligence Agency to kill Cuba's leader Fidel Castro.

The film reveals multiple methods of assassination, from exploding cigars to femmes fatales; a radio station rigged with noxious gas to a poison syringe posing as an innocuous fountain pen. Fabian Escalante, the former head of the Intelligence Directorate and the man who had the job of protecting Castro for many of the 49 years he was in power, alleges that there were over 600 plots and conspiracies known to Cuban agents, all dreamt up to end Castro's life. Some were perpetrated by the Central Intelligence Agency, especially during the first half of the 1960s. From the seventies onwards, the attempts were most often made by Cuban exiles who had been trained by the CIA shortly after Castro took power in 1959.

On the trail of Castro’s would-be killers, the filmmakers met a series of would-be assassins – several were also accused terrorists, still living openly in the United States. Orlando Bosch, accused by many of being the greatest terrorist in the Western Hemisphere, was found living peacefully in his Miami home, surrounded by an adoring family. Curiously, both Bosch and his companion-in-arms and fellow accused terrorist Luis Posada Carriles turned out to be keen amateur landscape painters.