Francesco Primaticcio (April 30, 1504 – 1570) was an Italian Mannerist painter, architect and sculptor who spent most of his career in France.

Born in Bologna, he trained under Giulio Romano in Mantua and became a pupil of Innocenzo da Imola, executing decorations at the Palazzo Te before securing a position in the court of Francis I of France in 1532.

Together with Rosso Fiorentino he was one of the leading artists to work at the Chateau Fontainebleau (where he is grouped with the so-called "First School of Fontainebleau") spending much of his life there. Following Rosso's death in 1540, Primaticcio took control of the artistic direction at Fontainebleau, furnishing the painters and stuccators of his team, such as Nicolò dell'Abate, with designs. He made cartoons for tapestry-weavers and, like all 16th-century court artists, was called upon to design elaborate ephemeral decorations for masques and fêtes, which survive only in preparatory drawings and, sometimes, engravings. Francis I trusted his eye and sent him back to Italy on buying trips in 1540 and again in 1545.

Giovanni Pierluigi da Palestrina (3 February 1525 or 2 February 1526 – 2 February 1594) was an Italian Renaissance composer of sacred music and the best-known 16th-century representative of the Roman School of musical composition. He had a lasting influence on the development of church music, and his work has often been seen as the culmination of Renaissance polyphony.

Palestrina was born in the town of Palestrina, near Rome, then part of the Papal States. Documents suggest that he first visited Rome in 1537, when he is listed as a chorister at the Santa Maria Maggiore basilica. He studied with Robin Mallapert and Firmin Lebel. He spent most of his career in the city.

Palestrina came of age as a musician under the influence of the northern European style of polyphony, which owed its dominance in Italy primarily to two influential Franco-Flemish composers, Guillaume Dufay and Josquin des Prez, who had spent significant portions of their careers there. Italy itself had yet to produce anyone of comparable fame or skill in polyphony.