Santa Maria del Popolo is an Augustinian church located in Rome, Italy. It stands to the north side of the Piazza del Popolo, one of the most famous squares in the city. The Piazza is situated between the ancient Porta Flaminia and the park of the Pincio. [The Porta Flaminia was one of the gates in the Aurelian Wall as well as the starting point of the Via Flaminia, the road to Ariminum (modern Rimini). The Via Flaminia was the most important route to the north of Ancient Rome.] The church includes works by several famous artists, architects and sculptors, for example Raphael, Gian Lorenzo Bernini, Caravaggio, Pinturicchio, Andrea Bregno, Guillaume de Marcillat and Donato Bramante.

In 1099, a chapel was built by Pope Paschal II to Our Lady, over a tomb of the Domitia family. Tradition has it that the site was haunted by Nero's ghost or demons in the form of black crows; therefore the pope chopped down the walnut tree sheltering the crows and built a church in its place. The name del Popolo ("of the people") probably derives from its funding by the people of Rome, but some sources say it comes from the Latin word populus, meaning "poplar" and referring to a tree located nearby. The chapel became a church by will of Pope Gregory IX, and given to the Augustinians, who still oversee the church, in the first half of 13th century.

Santa María (with diacritic over the "i") or Santa Maria may refer to:

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In the archipelago of the Azores: