Uithoorn ([ˌœy̆tˈɦoːrn] ( listen)) is a municipality and a town in the Netherlands, in the province of North Holland.

The municipality of Uithoorn consists of the following cities, towns, villages and/or districts: De Kwakel and Uithoorn.

The name De Uithoorn (or also De Uythoorn) was used at the end of the Middle Ages for the location of the lower courts of the deanery of Saint John. The village formed around its courthouse.

People depended on agriculture and animal husbandry. Agriculture became increasingly more difficult due to the steady soil subsidence. From circa 1600 on, peat extraction became important and resulted in the formation of large ponds, which in turn would be made into polders later on.

During the Franco-Dutch War in the "disaster year" of 1672, Uithoorn was on the front lines and fortifications were built.

During the Batavian Republic period, the neighbouring village of Thamen was merged with Uithoorn. Its economy was limited but improved in the middle of the 19th century when some industries (including chemical) were established in the area. The reclamation of a few large ponds provided extra agricultural land at the end of the same century.