T-cell Lymphoma

Histopathology Lymph node--Peripheral T-cell lymphoma, unspe

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Duration: 1:13
Published: 11 May 2007
Uploaded: 28 May 2011
Author: WashingtonDeceit

Histopathology Lymph node--Peripheral T-cell lymphoma, unspecified (mixed medium-sized and large cell)

Basics About Peripheral T-Cell Lymphoma

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Duration: 8:43
Published: 28 Jan 2010
Uploaded: 03 Aug 2011
Author: pharmatechoncology

Information about this Non-Hodgkins Lymphoma and available treatments, including clinical trials. Visit our website for more information: www.pharmatechoncology.com

T-Cell Lymphoma Clinic Trials

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Duration: 1:47
Published: 07 Jul 2011
Uploaded: 13 Jul 2011
Author: mdandersonorg

Our mission is to improve the cure rate of patients with PTCL and reduce treatment-related toxicity by developing novel targeted therapy using rationally designed small molecules, antibodies and combination regimens of biologic agents. For referrals, please contact ayounes@mdanderson.org or Amanda Copeland at ARCopeland@mdanderson.org.

Skin Cancer Cutaneous T-cell Lymphoma Treatment

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Duration: 2:51
Published: 04 May 2010
Uploaded: 27 Aug 2010
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Treatment. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! The treatment for CTCL depends on the stage at which the disease is diagnosed. The prognosis is extremely variable and also depends on the stage at diagnosis. Early patch stage CTCL can be indolent, with no progression for years and the disease may be cured. Treatment may be directed to the whole body so that undetected lesions will be treated. These lesions may temporarily become more apparent during therapy and then resolve. Treatments for patch and plaque stage disease include application of topical steroids, topical chemotherapy with nitrogen mustard, topical retinoids and PUVA. PUVA is the combination of oral psoralen with UVA light phototherapy. The drug makes the skin more responsive to UVA rays. Patients receiving UVB or PUVA are treated 3 times per week, until remission is achieved. Treatments are tapered. Monthly maintenance therapy may be continued for years. Broad band and narrow band ultraviolet light B can also keep the disease in check and may prevent progression. Topical nitrogen mustard can be used to treat patch or plaque stage disease. The medication is prepared as a liquid or cream and is applied by the patient. The amount is increased as tolerance develops. This therapy can induce long-term remission and even cures. Nitrogen mustard therapy can be used in combination with phototherapy or total body electron beam ...

Skin Cancer Cutaneous T-cell Lymphoma Hematology and pathology

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Duration: 2:40
Published: 04 May 2010
Uploaded: 09 Nov 2010
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Hematology and pathology. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Mycosis fungoides and the Sezary syndrome are cutaneous T-cell lymphomas. These are characterized by the expansion of a clone of malignant CD4 helper T-cells that have a propensity to home and accumulate in the skin, lymph nodes, and peripheral blood. Confirming the diagnosis of mycosis fungoides is difficult in the early stages of the disease. The clinician will biopsy patch stage lesions and ask the pathologist to rule out MF. The classic features of the disease are usually absent at this stage. Typically a few atypical lymphocytes are seen and the pathologist reports an atypical lymphocytic infiltrate, suspicious for MF. Biopsy in patch-or-plaque stage shows a lymphocytic infiltrate in the superficial dermis, with individual lymphocytes migrating among epidermal keratinocytes. The affinity of the malignant T-cells to migrate to the epidermis is called epidermotropism. The lymphocytes are pleomorphic, hyperchromatic, and have hyperconvoluted nuclei. Staining of skin-biopsy specimens with a panel of lymphocyte markers is used sub classify the clone of cells. Immunohistochemistry and molecular genetics have demonstrated aberrant expression of the T lymphocyte surface antigens. The neoplastic T helper CD4 positive cells show gene rearrangements of the T cell receptors, usually of the alpha receptors. Biopsys taken at ...

Skin Cancer Cutaneous T-cell Lymphoma Erythrodermic stage (Sezary syndrome)

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Duration: 1:17
Published: 04 May 2010
Uploaded: 21 Apr 2011
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Erythrodermic stage (Sezary syndrome). See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Erythrodermic patients, present with total body redness. This presentation of CTCL is called the Sezary syndrome. The differential diagnosis of erythroderma includes psoriasis, pityriasis rubra pilaris, seborrheic dermatitis, and severe drug reactions. The erythrodermic stage can progress from any stage or appear without any previous skin findings. The skin is diffusely red and scaly. The palms and soles may become very thick and crack, making it difficult to walk. Alopecia and ectropion are common, exfoliation and heat loss thru the skin are worrisome and infiltration of the lymph nodes occurs. Many of these patients have generalized pruritus and shaking chills at presentation. There are more than 1000 per mm3 atypical T lymphocytes with cerebriform nuclei circulating in the peripheral blood. SS occurs in 5% of all cases of MF.

Skin Cancer Cutaneous T-cell Lymphoma Definition and Description

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Duration: 1:53
Published: 03 May 2010
Uploaded: 07 Oct 2010
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Definition and Description. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! In 1806, the term mycosis fungoides (MF) was first used to described a disease with large necrotic skin tumors that resembled mushrooms. The term cutaneous T-cell lymphoma (CTCL) is now used to describe a group of malignant T-cell lymphomas with primary manifestations in the skin. MF is the most common type of CTCL. Sezary syndrome (SS) is the leukemic form of MF. Cutaneous T-cell lymphoma is a specific T-cell lymphoma of the skin that can invade the lymph nodes, peripheral blood and internal organs. CTCL is a clonal lymphoid malignancy of helper T lymphocytes. There are several stages of CTCL pre-mycosis fungoides, patch stage, plaque stage tumor stage and an erythrodermic form called Sezary syndrome. All of these stages can be progressive and cause death. The cause is unknown. The incidence of CTCL is about 1 in 100000. It is more common in men than women. CTCL is more common in African-Americans than Caucasians. Most cases are diagnosed in the 5th and 6th decades of life. The prognosis of CTCL is related to the stage at which the disease is diagnosed.

3T image challenge - February 2010 - NK T-Cell Lymphoma

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Duration: 1:19
Published: 11 Feb 2010
Uploaded: 27 Mar 2011
Author: 3TForMe

Big Sky Diagnostic Imaging's 3T image challenge for February 2010. This case is presented by radiologist, Dr. Rex Dietz. This case features an MRI of the head, particularly the sinus/nasal region. This patient has NK T-Cell Lymphoma.

PTCL - Peripheral T-Cell Lymphoma

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Duration: 4:24
Published: 10 Jun 2010
Uploaded: 10 Jun 2010
Author: OncUViewTV

Jill P. Atmar, RN, ANP from the Dept. of Lymphoma and Myeloma MD Anderson Cancer Center talks about PTCL - ONS 2010

Skin Cancer Cutaneous T-cell Lymphoma Tumor stage

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Duration: 0:24
Published: 04 May 2010
Uploaded: 11 Jan 2011
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Tumor stage. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Tumor stage lesions are large, darker brown, red to gray expanding nodules that vary in size. The face and body folds are usually the sites of tumor development. The tumor may ulcerate and become infected. The prognosis is poor.

Skin Cancer Cutaneous T-cell Lymphoma Patch Stage

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Duration: 1:03
Published: 04 May 2010
Uploaded: 03 Jul 2011
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Patch Stage. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Early patch stage CTCL can resemble eczema or atopic dermatitis and may be misdiagnosed for years. Unlike eczema, these lesions are rarely pruritic. The flat, pink to red scaly atrophic, mottled telangiectatic patches occur primarily on the lower trunk, thighs, and breasts in women. They may be fixed and stable for years and may resolve spontaneously. Patches vary in size. Early on in the disease, the histology may not be diagnostic. On average, 3 to 6 large excisional biopsies over 6 months, may be required to confirm the diagnosis. Persistent eczema or unresponsive inflammatory skin diseases should have a biopsy to confirm the diagnosis and rule out CTCL.

A Team Approach for Treating T-Cell Lymphoma

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Duration: 3:06
Published: 30 Jun 2011
Uploaded: 06 Jul 2011
Author: mdandersonorg

Of the approximately 76000 new patients who will be diagnosed with non-Hodgkin lymphoma (NHL) this year, 15% will have peripheral T-cell lymphoma (PTCL). To meet these challenges, we've assembled a world-class team of medical oncologists, dermatologists, radiation therapists, hematopathologists and stem cell transplant experts to create a multidisciplinary T-cell lymphoma working group. Chaired by Younes, the group discusses challenging cases and recent clinical and pre-clinical data in PTCL, in addition to new concepts to design and conduct innovative clinical trials for PTCL patients. For referrals, please contact ayounes@mdanderson.org or Amanda Copeland at ARCopeland@mdanderson.org.

Diagnostic Challenges in Cutaneous T-Cell Lymphoma

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Duration: 2:15
Published: 30 Mar 2010
Uploaded: 27 Aug 2010
Author: ElsGlobalMedicalNews

Dr. John Zic of Vanderbilt University discusses controversies in cutaneous T cell lymphomas, particularly the difficulties in diagnosis.

I SURVIVED THREE CANCERS TESTICULAR CARCINOID AND T CELL LYMPHOMA

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Duration: 2:38
Published: 12 Jun 2010
Uploaded: 05 Aug 2010
Author: manofcancer

HIT ON LINK www.carcinoidwade.com cancers lung cancer cancer treatment cancer treatments cancer therapy liver cancer pancreas cancer cancer hospital cancer symptoms prostate cancer cancer tumor cancer prostate cancer diagnosis cancer chemotherapy cancer about cancer beat cancer secondary...

Skin Cancer Cutaneous T-cell Lymphoma Plaque stage

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Duration: 0:31
Published: 04 May 2010
Uploaded: 09 Nov 2010
Author: SkinDiseaseEducation

Dr. Shane Chapman, MD discusses Skin Cancer Cutaneous T-cell Lymphoma Plaque stage. See more at www.dermnet.com PLEASE RATE AND COMMENT!!! Plaque stage CTCL lesions become red to brown, and elevated. Malignant cells multiply and the lesions thicken and show textural changes. They are most often found in the bathing trunk area. These plaques are variably round to oval and arciform or serpiginous. A single biopsy usually confirms the diagnosis at this stage.

Cellular animation.Neoplastic and T Cell.

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Duration: 1:55
Published: 15 Jun 2010
Uploaded: 29 Jul 2011
Author: miapham

This was a 5 minute piece that has been edited down to the fun parts. The animation had voice over that explained intracellular activity of a cancer cell, and the how a specific name brand drug would treat it.

Questions and Answers on Follicular lymphoma from Fredrick Hagemeister, MD

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Duration: 8:03
Published: 10 Jul 2009
Uploaded: 13 Jul 2011
Author: mdandersonorg

Lymphoma is a cancer of the bodys lymphocytes, a type of white blood cell. After the cells become malignant (cancerous), they can become tumor masses that invade other organs. T cell lymphomas are relatively uncommon in the United States. They are more common in Asia. B-cell lymphomas are relatively common in the United States and Europe. They can occur in the young and the old, and, depending on their genetic makeup, can be fast- or slow-growing. The hallmark of follicular lymphoma is its slowly progressive nature. Few patients have symptoms until they visit their doctors with swollen lymph nodes. Though it usually is slow-growing, the disease can be tricky, finding ways to recur again and again. Fortunately, new drugs and targeted agents offer hope to patients. Answering questions about follicular lymphoma is Fredrick Hagemeister, MD, professor in the Department of Lymphoma and Myeloma at MD Anderson.

French Bulldog-Churchill tribute

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Duration: 3:01
Published: 14 Jul 2007
Uploaded: 03 Aug 2011
Author: texasotts

Since youtube has chosen to take the music off of all my videos but continue to allow people to dance to music in the background, sing music that is copywrited and so on I have moved all my material over to onetruemedia so you can view the vidoes with the music at www.onetruemedia.com collection of pictures of my foster dog Churchill that passed away much too soon of Cutaneous T-cell Lymphoma. He will be dearly missed. I have been amazed at the feedback I have had so I have added some additional information- Churhcill was a foster dog that was taken to a shelter to be euthanized by his owners, FBRN came to the rescue to save this boy, we took him to see a dermatologist to get the diagnosis of Cutaneous T-Cell Lymphoma which is a rare skin cancer and then went to see an oncologist for information on Chemo. Churchill was too far and was dying and the chemo would not start to work for 3 months and he did not have three months left so we opted to let him go peacefully to end his suffering. I hope that the couple of months he was with us that he was happy and we loved him very much. Churchill was cremated and remains with me so that he knows he has found his forever home. Thank you to everyone for all the kind words. You too can help change or save a life by volunteering at a rescue of your choice.

PRAYING FOR BROOKE

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Duration: 5:07
Published: 06 Feb 2008
Uploaded: 08 Jul 2011
Author: TTHORN98259

BROOKE IS 12 YEARS OLD WAS DIAGNOSED WITH T-CELL LYMPHOMA DEC 2007 AND HAS 2 YEARS OF CHEMO AHEAD OF HER . PLEASE PRAY FOR OUR FRIEND BROOKE

CheckOrphan NewsFlash November 11, 2009

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Duration: 4:16
Published: 11 Nov 2009
Uploaded: 20 Aug 2010
Author: CheckOrphan

CheckOrphan NewsFlash for Wednesday, November 11, 2009 - breaking news about rare diseases, orphan diseases, orphan drugs, and neglected diseases. Today's broadcast highlights topics about: Multiple Sclerosis, American Academy of Neurology, Neuromyelitis Optica, Devic Disease, Victoria Jackson, Guthy-Jackson Charitable Foundation, Type 1 Myotonic Dystrophy, DM1, Steinarts disease, Pentamidine, PNAS, University of Michigan, Kellogg Eye Center, Rituximab, Graves eye disease, Ikano Therapeutrics, epilepsy, midazolam, epileptic seizure, Daval International, Amyotrophic Lateral Sclerosis, Lou Gehrig Disease, AIMSPRO, Krabbe Leukodystrophy, Krabbes Disease, Sunesis, orphan drug desigation, Voreloxin, Acute Myeloid Leukemia, T-cell lymphoma, FDA, Istodax, Gloucester Pharmaceuticals, CheckOrphan, NewsFlash www.checkorphan.org www.checkorphan.org/content/newsflash www.guthyjacksonfoundation.org

30 Young Cancer Warriors (Version #5)

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Duration: 9:22
Published: 16 Jul 2010
Uploaded: 16 Jul 2011
Author: lilliesha

This is just a few of the thousands of children battling cancer every day... They are our inspirations and are who we are fighting for 1, ^^Abbie Waters^^ -- Rhabdomyosarcoma 2, Lexi Covert -- Pilomyxoid Astrocytoma www.carepages.com 3, Adriana Gunty -- Neuroblastoma www.caringbridge.org 4, Georgia Hillman -- Wilms Tumour 5, ^^Miranda Berry^^ -- Ewing's Sarcoma www.carepages.com 6, ^^Jed Suckling^^ -- Pilomyxoid Astrocytoma 7, Melissa Joyner -- T-cell Lymphoma www.caringbridge.org 8, Zachary Hartsell -- Ewing's Sarcoma www.caringbridge.org 9, Natalie Berg -- Rhabdomyosarcoma www.caringbridge.org 10, Rachel Collett -- Osteosarcoma www.carepages.com 11, Sadie Jeffcoat -- Juvenile Pilocytic Astrocytoma www.caringbridge.org 12, Gabriella Garcia -- Neuroblastoma www.carepages.com 13, Madison Lehman -- Burkitt's Lymphoma www.caringbridge.org 14, Karlie Spurlin -- Medulloblastoma www.caringbridge.org 15, Jackie Doodle -- Wilms Tumor www.caringbridge.org 16, Michael Mider -- Wilms Tumor www.caringbridge.org 17, Yano Pournaras -- Neuroblastoma www.caringbridge.org 18, Natalie Burraston -- ALL www.caringbridge.org 19, Roisin Wells -- DIPG www.facebook.com 20, Samuel Adams -- pre-B ALL www.caringbridge.org 21, August Williams -- t-cell ALL www.caringbridge.org 22, Brianna Moore -- High Grade Mixed Gleuronal www.caringbridge.org 23, Jonah White -- Osteosarcoma www.caringbridge.org 24, ^^Amanda Peebles^^ -- Aplastic Anemia, B-cell Lymphoma www.carepages.com 25, Scott Lawford ...

Mantelcell Lymphoma Cancer Testimonial

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Duration: 2:04
Published: 11 Jun 2009
Uploaded: 27 Aug 2010
Author: DrPabloXYZ

XYZ-Wellbeing Testimonial Mantel Cell Lymphoma Cancer, This unique program offered home instruction or you can register for the ReTreat Facility Cancer Trial. Ozone, Laetrile, Cesium-High PH Therapy, Hyperbaric Oxygen, Colonic all play a role.

Allos Therapeutics (ALTH) to Receive Payment of $50M from Collaboration with Mundipharma for FOLOTYN

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Duration: 2:20
Published: 10 May 2011
Uploaded: 10 May 2011
Author: crwenewswire

Lymphoma is a type of cancer involving cells of the immune system, called lymphocytes — I'm Christina Collins with CRWE Newswire — Today's company highlight is Allos Therapeutics Incorporated, trading with the symbol ALTH —Allos Therapeutics Incorporated is a biopharmaceutical company committed to the development and commercialization of innovative anti-cancer therapeutics— Allos is currently focused on the development and commercialization of FOLOTYN,- pralatrexate injection,- a folate analogue metabolic inhibitor— FOLOTYN is the first and only drug approved in the US for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma, a biologically diverse group of aggressive blood cancers —-T-cell lymphomas comprise a biologically diverse group of blood cancers that account for approximately 10% to 15% of all cases of non-Hodgkin lymphomas— Allos Therapeutics estimates the current annual incidence of Peripheral T-Cell Lymphoma to be approximately 5900 patients in the US and approximately 6000-7000 patients in the top five European markets—Allos Therapeutics and Mundipharma International Corporation Limited jointly reported recently that they have entered into a strategic collaboration agreement to co-develop FOLOTYN— Under the agreement, Allos retains full commercialization rights for FOLOTYN in the United States and Canada, with Mundipharma having exclusive rights to commercialize FOLOTYN in all other countries—Under the collaboration, Allos ...

T-cell lymphoma

Types

Epidemiology

See also

References