A Greek–English Lexicon is a standard lexicographical work of the Ancient Greek language.

The lexicon was begun in the nineteenth century and is now in its ninth (revised) edition. Based on the earlier Handwörterbuch der griechischen Sprache by the German lexicographer Franz Passow (first published in 1819, fourth edition 1831), which in turn was based on Johann Gottlob Schneider's Kritisches griechisch-deutsches Handwörterbuch, it has served as the basis for all later lexicographical work on the ancient Greek language, such as the ongoing Greek–Spanish dictionary project Diccionario Griego–Español (DGE).

It was edited by Henry George Liddell, Robert Scott, Henry Stuart Jones and Roderick McKenzie, and published by the Oxford University Press. It is now conventionally referred to as Liddell & Scott, Liddell–Scott–Jones, or LSJ, and its three sizes are sometimes referred to as "The Little Liddell", "The Middle Liddell" and "The Big Liddell" or "The Great Scott".

According to Stuart Jones's preface to the ninth (1925) edition, the creation of the Lexicon was originally proposed by David Alphonso Talboys, an Oxford publisher. It was apparently published by the Clarendon Press at Oxford rather than by Talboys because he retired from the publishing business before the first edition (1843) was complete. The second through sixth editions appeared in 1845, 1849, 1855, 1861, and 1869.