East Garden City is a census-designated place (CDP) in the northeast part of the Town of Hempstead, in the central part of Nassau County, New York, along the Hempstead/North Hempstead town line. The population was 6,028 at the 2010 census. East Garden City is a hamlet (an unincorporated area) and a mostly commercial and industrial area.

East Garden City is located at 40°43′51″N 73°35′53″W / 40.73083°N 73.59806°W / 40.73083; -73.59806 (40.730790, -73.598050).

Beginning on its northern border and proceeding clockwise, the hamlet of East Garden City in the Town of Hempstead is bordered on the north by the hamlet of Carle Place and the Village of Westbury in the Town of North Hempstead (the Hempstead/North Hempstead town line); on the east by the hamlet of East Meadow; on the south by the hamlet of Uniondale and the Village of Hempstead; and, on the west by the Village of Hempstead and the Village of Garden City.

East Garden City is one of those many villages and hamlets on Long Island where none of the places in the community have the hamlet name as part of their mailing address: places in the hamlet of East Garden City have either a "Garden City, NY 11530", a "Westbury, NY 11590", a "Uniondale, NY 11553" or a "Hempstead, NY 11550" mailing address.