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The Los Angeles Times08 May 2013
George Palade of Rockefeller refined both techniques and used them to discover ribosomes, the cellular compartments where proteins are synthesized, and the endoplasmic reticulum, an extensive network in the cell that carries ribosomes and transports materials needed by the cell ... Novikoff of the Albert Einstein College of Medicine used the electron microscope to image lysosomes in partially purified cellular fractions....(size: 9.3Kb)
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Fox News20 Mar 2013
Heart stem cell therapy after a major heart attack holds the promise of helping to repair severely damaged cells by encouraging the growth of new ones ... Now, that problem could be potentially solved with a new visualization technique developed by Dr ... ... “Luckily, when we put the nanoparticles inside the cells, they aggregated together into larger structures inside of the cellular compartments,” Jokerst said ... Share This Article ... ....(size: 5.7Kb)
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PhysOrg13 Mar 2013
Starvation and the use of anti-inflammatory steroid drugs can induce muscle wasting in animals ... More specifically, these stimuli increased the expression of the Mul1 protein ... When the researchers overexpressed Mul1 in muscle cells, instead of fusing with other mitochondria, these organelles merged with a cellular compartment called the lysosome in which proteins and organelles are degraded ... ....(size: 2.1Kb)
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noodls21 Feb 2013
Patricia Keely, professor of cell and regenerative biology, focuses on how cellular interactions with the extracellular matrix are altered during carcinogenesis, to result in invasive, metastatic carcinoma ... Marisa Otegui, associate professor of botany, works on the way cells control the flow of proteins between different cellular compartments and the regulatory effects of these cellular tracking events on plant development....(size: 4.1Kb)
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Newstrack India13 Feb 2013
Tweet. Washington, February 13 (ANI). A new study led by an Indian-origin researcher suggests that a master regulator protein may explain the development of aberrant cell growth in the pancreas spurred by inflammation ... Broadly speaking, two cellular compartments are important in a normal pancreas, endocrine cells, which produce hormones including insulin, and exocrine cells - acinar and ductal-which make and secrete digestive enzymes ... ....(size: 2.3Kb)
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PhysOrg12 Feb 2013
Broadly speaking, two cellular compartments are important in a normal pancreas, endocrine cells, which produce hormones including insulin, and exocrine cells – acinar and ductal—which make and secrete digestive enzymes ... They used cell lineage tracing to follow what happens to the regulator protein called Prrx1 as cells change characteristics ... Inflammation is Key Culprit ... But, if the pancreatitis is chronic, changed cells stay changed ... ....(size: 2.3Kb)
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PhysOrg04 Feb 2013
The results of the studies now published in the journal Nature show that the structural architecture and the main operation mode of the Exosome are conserved in all domains of life ... A ubiquitous molecular shredder ... In the future, the researchers want to understand how the Exosome is selectively targeted by the RNAs earmarked for degradation and how it is regulated in the different cellular compartments. ....(size: 2.3Kb)
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PhysOrg01 Feb 2013
31 online edition of Science, Ting and colleagues used the new technique to identify nearly 500 proteins located in the mitochondrial matrix—the innermost compartment of the cellular organelle where energy is generated ... Previous attempts to map the matrix proteome by extracting that cellular compartment and then performing mass spectrometry yielded a list of only 37 proteins....(size: 6.0Kb)
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noodls31 Jan 2013
31 online edition of Science, Ting and colleagues used the new technique to identify nearly 500 proteins located in the mitochondrial matrix - the innermost compartment of the cellular organelle where energy is generated ... Previous attempts to map the matrix proteome by extracting that cellular compartment and then performing mass spectrometry yielded a list of only 37 proteins....(size: 8.0Kb)
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PhysOrg19 Dec 2012
Wip1 is a phosphatase, an enzyme that specializes in the targeted removal of phosphate chemical groups that modulate function of proteins such as Atm and p53 ... This requires the cells to physically liberate cholesterol molecules from lipid droplets; Wip1 promotes this by stimulating a mechanism called 'autophagy', wherein lipid droplets are absorbed into cellular compartments, known as lysosomes, and broken down enzymatically ... ....(size: 2.3Kb)
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PhysOrg27 Nov 2012
The process uses a computational model to generate predictions about the dynamics of cell receptors in different cellular compartments. The model predicted that the time scales of receptor (de)activation kinetics on the cell surface and the interior compartments were comparable ... Since knowing their differential cellular signaling patterns can provide ......(size: 3.0Kb)
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Yahoo Daily News04 Oct 2012
“We are delighted that our preclinical contract research expertise has yet again proven useful,” said Dr. Christophe Echeverri, CEO/CSO of Cenix ... Holger Bock, CEO of ugichem ... About Cenix BioScience ... http.//www.cenix.com ... As a result cells currently inaccessible with standard gene silencing technologies or even defined cellular compartments become targetable by Ugimers without the need for additional delivery tools ... Contact. Dr ... ....(size: 11.1Kb)