NBA 2K1 is the second installment of the NBA 2K series. It was developed by Visual Concepts and published by SEGA (as Sega Sports). It was the first NBA 2K game to feature online multiplayer and the first game to feature street courses instead of playing a game inside the stadium in the first game, famous street courts such as The Cage, Rucker Park, Franklin Park^{[disambiguation needed ]}, and the Goat Park. It was released on November 1, 2000 in North America with the Dreamcast.

In a Japanese release pack, you can get the NBA 2K1 Bible. It basically is a handbook for beginners of the game. It may only have been sold in Japan, but it is more than likely unknown if it was sold in any other country.

The cover athlete was featured as Allen Iverson of the Philadelphia 76ers until the release of ESPN NBA 2K5.

On release, Famitsu magazine scored the Dreamcast version of the game a 30 out of 40.