Tempora mutantur
Tempora mutantur is a Latin adage meaning "times change". It is also stated in various longer hexametric forms, most commonly Tempora mutantur, nos et mutamur in illis, meaning "Times change, and we change with them". The phrase is not found in Classical Latin, but is a variant of phrases of Ovid, to whom it is sometimes misattributed. Instead, it dates to early/mid 16th century Germany, in the context of the Protestant Reformation, and it subsequently was popularized in various forms. See history for history and other forms.
Wording
Regarding the form:
Like many adages and proverbial or wisdom maxims drawn from the Latin cultural tradition, this line is a hexameter: the rhythmical verse, typical of the great epic poetry, both in Greek and Latin literature. All other Latin verses cited in this page are hexameters as well.
The fact that et (and) is following nos and being accented in the hexameter's rhythm, attributes an emphasis to it. In this position et works as a short form of etiam; meaning: "also, too" or "even". So a correct translation is "and we too", instead of the simple "and we".