Alzheimer's disease (AD), also known in medical literature as Alzheimer disease, is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. It was first described by German psychiatrist and neuropathologist Alois Alzheimer in 1906 and was named after him.

Most often, AD is diagnosed in people over 65 years of age, although the less-prevalent early-onset Alzheimer's can occur much earlier. In 2006, there were 26.6 million sufferers worldwide. Alzheimer's is predicted to affect 1 in 85 people globally by 2050.

Although Alzheimer's disease develops differently for every individual, there are many common symptoms. Early symptoms are often mistakenly thought to be 'age-related' concerns, or manifestations of stress. In the early stages, the most common symptom is difficulty in remembering recent events. When AD is suspected, the diagnosis is usually confirmed with tests that evaluate behaviour and thinking abilities, often followed by a brain scan if available.

Charles Peete "Charlie" Rose, Jr. (born January 5, 1942) is an American television talk show host and journalist. Since 1991 he has hosted Charlie Rose, an interview show distributed nationally by PBS since 1993. He has also co-anchored CBS This Morning since January 2012. Rose, along with Lara Logan, has hosted the revived CBS classic Person to Person, a news program during which celebrities are interviewed in their homes, originally hosted from 1953 to 1961 by Edward R. Murrow.

Rose was born in Henderson, North Carolina, the only child of Margaret Frazier and Charles Peete Rose, Sr., tobacco farmers who owned a country store. As a child, Rose lived above his parents' store in Henderson and helped out with the family business from age seven. Rose admitted in a Fresh Dialogues interview that as a child his insatiable curiosity was constantly getting him in trouble. A high school basketball star, Rose entered Duke University intending to pursue a degree with a pre-med track, but an internship in the office of Democratic North Carolina Senator B. Everett Jordan got him interested in politics. Rose graduated in 1964 with a bachelor's degree in history. At Duke, he was a member of the Kappa Alpha Order fraternity. He earned a Juris Doctor from the Duke University School of Law in 1968. He met his wife, Mary (née King), while attending Duke.