The Crossroads Centre is a drug and alcohol addiction rehabilitation centre located on the Caribbean island of Antigua. The centre was founded by guitarist Eric Clapton & Richard Conte, CEO of The Priory Hospitals Group (London) and Transitional Hospitals Corporation (Nevada). All development of the facility was performed by officers and employees of these 2 companies. Conte & Clapton served as the Centre's first two board members with Conte being chairman. Transitional put up all working capital during the development phase and the facility was initially owned 2/3 by Transitional and 1/3 by Clapton. Former prime minister Lester Bird of Antigua was integrally involved by Transitional and arranged for the government of Antigua's assistance with roads, utilities and a favorable land purchase price. Conte's wife is credited with naming the facility and his associate Lester Keizer of Transitional was the 'point man' on the project.

Eric Patrick Clapton, CBE, (born 30 March 1945) is an English guitarist and singer-songwriter. Clapton is the only three-time inductee to the Rock and Roll Hall of Fame: once as a solo artist, and separately as a member of The Yardbirds and Cream. Clapton has been referred to as one of the most important and influential guitarists of all time. Clapton ranked second in Rolling Stone magazine's list of the "100 Greatest Guitarists of All Time" and fourth in Gibson's Top 50 Guitarists of All Time.

In the mid 1960s, Clapton departed from the Yardbirds to play blues with John Mayall & the Bluesbreakers. In his one-year stay with Mayall, Clapton gained the nickname "Slowhand". Immediately after leaving Mayall, Clapton formed Cream, a power trio with drummer Ginger Baker and bassist Jack Bruce in which Clapton played sustained blues improvisations and "arty, blues-based psychedelic pop." For most of the 1970s, Clapton's output bore the influence of the mellow style of J.J. Cale and the reggae of Bob Marley. His version of Marley's "I Shot the Sheriff" helped reggae reach a mass market. Two of his most popular recordings were "Layla", recorded by Derek and the Dominos, another band he formed and Robert Johnson's "Crossroads", recorded by Cream. A recipient of seventeen Grammy Awards, in 2004 Clapton was awarded a CBE for services to music. In 1998, Clapton, a recovering alcoholic and drug addict, founded the Crossroads Centre on Antigua, a medical facility for recovering substance abusers.

Sheryl Suzanne Crow (born February 11, 1962) is an American singer-songwriter, record producer, musician, and actress. Her music incorporates elements of rock, folk, hip hop, country and pop. She has won nine Grammy Awards from the National Academy of Recording Arts and Sciences.

She has performed with The Rolling Stones and has sung duets with Mick Jagger,Michael Jackson, Eric Clapton, Luciano Pavarotti, John Mellencamp, Kid Rock, Michelle Branch, and Sting among others. She has performed backing vocals for Tina Turner, Michael Jackson, Don Henley and Belinda Carlisle. She also sang as part of the back up vocals for the Bob Dylan 30th Anniversary celebrating Dylan's 30 years as a recording artist. Crow has released seven studio albums, two compilations, and a live album, and has contributed to film soundtracks. She has sold 16 million albums in the United States and 35 million albums worldwide and her newest album, 100 Miles from Memphis, was released on July 20, 2010. Recently she appeared on NBC's 30 Rock, ABC's GCB and Cougar Town, Disney Channel's Hannah Montana Forever, and Jon Stewart and Stephen Colbert's Rally to Restore Sanity and/or Fear.