The Cuyo Archipelago or Cuyo Islands, is a group of about 45 islands lying to the northeast of the Philippines island of Palawan. It lies south of Mindoro and between Northern Palawan and Panay. It is centered around the largest island of the archipelago, the island of Cuyo, with an area of 22 square miles (57 km²) and is about 9 miles (14 km) long.

The 45 islands and islets of the archipelago form a total land area of 50 square miles (130 km²). Cuyo is divided into two island groups. Up north is the Quiniluban group. To the south is the Cuyo group, where the centers of the three municipalities namely Cuyo, Agutaya, and Magsaysay are located.

Geologically, the islands are related to the main island of Palawan. They are positioned on the western edge of the Luzon Arc. Cuyo island is volcanic. The northern islands of Quiniluban seem to be uplifted coral atolls, although the heights of some of the peaks strongly suggest volvanic uplift. Many other islands of the group are purely corallian.

Cuyo is divided in three municipalities, namely Cuyo, Agutaya, and Magsaysay: