The Master Control Facility (MCF)(Hindi:मुख्य नियंत्रण सुविधा) is a facility set up by the Indian Space Research Organisation (ISRO) in the city of Hassan in the Indian state of Karnataka. Established in 1982, this facility is responsible for monitoring and controlling the satellites launched by ISRO. This was the only Master Control Facility of ISRO till another one was established in Bhopal in 2005.

When ISRO wanted to establish a control facility, it inspected various sites that were offered to it within India. ISRO chose Hassan as the location (Location on Google Maps) because it was free of noise and encountered less terrestrial transmission than other proposed sites. Low interference was a must since the facility should be able to pick up even very weak signals from the satellite. The land to set up this facility was spread across 17.2 hectares and offered by the Government of Karnataka.

The MCF has three internal divisions; the Spacecraft Control Centre, Mission Control Centre and the Earth station.