Receptor tyrosine-protein kinase erbB-3 is an enzyme that in humans is encoded by the ERBB3 gene.

This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized.

Chase & Status are an Electronic music production duo consisting of Saul Milton (Chase) and Will Kennard (Status). In addition, MC Rage & Andy Gangadeen also make up the live band. The duo hail from London and formed in 2003 after meeting at university in Manchester. The duo have since released two studio albums as well as collaborating with major artists such as Cee Lo Green, Rihanna, Example and Tinie Tempah.

Saul Milton (Chase) and Will Kennard (The Status) originally met in Manchester, England whilst studying at the cities universities, reminiscent of past music groups such as the Chemical Brothers. Milton went to the Victoria University of Manchester and studied History of Art while Kennard studied English and Humanities at Manchester Metropolitan. Both decided to drop out of university to pursue a music career.

They released some material on various labels dealing with drum and bass music, including Renegade Hardware. In particular, the tracks "Barbarians" and the remix of Future Cut's "20/20" were received well by the scene. They released an EP called "Ten Tonne EP", and they had some collaborations with other artists in the scene.

James Patrick "Jim" Moran, Jr. ( /mɵˈræn/; born May 16, 1945) is the U.S. Representative for Virginia's 8th congressional district, serving since 1991. He is a member of the Democratic Party. The district is located in Northern Virginia and includes the cities of Falls Church and Alexandria, all of Arlington County, and a portion of Fairfax County.

Jim Moran was the mayor of Alexandria, Virginia for five years from 1985 to 1990, when he resigned to run for Congress. He defeated Republican incumbent Stanford Parris in the general election on November 6, 1990, and was sworn in the following January. Since then he has served ten consecutive terms as a member of the Congress. He is of Irish descent and is the son of professional football player James Patrick Moran, Sr. and the brother of Democratic Party of Virginia Chairman Brian Moran.

Moran, the oldest of seven children, was born in Buffalo, New York, and grew up in Natick, Massachusetts, a working-class suburb west of Boston. His parents were Dorothy (Dwyer) and James Patrick Moran, Sr., a professional football player for the Boston Redskins in 1935 and 1936; outside of football he worked as a probation officer. Both his father and mother were Roosevelt Democrats and supporters of the New Deal. Moran attended Marian High School in Framingham, Massachusetts.