Brandon Fusco (born July 26, 1988) is an American football center for the Minnesota Vikings of the National Football League. He was drafted by the Vikings with the 172nd overall pick in the sixth round of the 2011 NFL Draft. He played college football at Slippery Rock University of Pennsylvania.

Fusco attended Seneca Valley High School in Harmony, Pennsylvania, where he played offensive tackle. He did not play until his junior year at Seneca Valley, stating "Sophomore year, didn’t really do nothing and football just kind of came to my attention. I always watched it on TV and I sometimes got into a ticked off mood so I wanted to get out on the field and take my frustrations out on people." Despite performing for a team that won just one of eighteen contests during his two varsity seasons, Fusco earned All-WPIAL Class AAA-1 and honorable mention Quad North All-Star honors. Fusco was also an honor roll student.

Fusco was not heavily recruited out of high school, mainly due to his lack of prep school experience and his 6-4, 240 lbs frame. He was only offered a chance to play football at Division II schools, Youngstown State and Slippery Rock being the leading candidates. He eventually chose to enroll at Slippery Rock, stating that he felt very connected with the coaching staff.