Snuppy (Korean: 스너피 a portmanteau of "SNU" and "puppy" also known as "doggy"; born April 24, 2005)^[1] is an Afghan hound, credited with being the world's first cloned dog. The puppy was created using the cell of an ear from an adult Afghan hound and involved 123 surrogate mothers, of which only three produced pups (Snuppy being the sole survivor). The team of 45 responsible for cloning Snuppy was led by biomedical scientist Hwang Woo-Suk, who was later found to have lied about his research on previous projects, however independent investigators discovered that Snuppy was a true clone. Snuppy has since been used in the first known successful breeding between cloned canines, after his sperm was used to artificially inseminate two cloned females, which resulted in the birth of 10 puppies in 2008. Replacement team leader and veterinarian Yi Byeong-cheon used this technology to clone the first sterilized working dogs, Toppy.

History[link]

After Dolly the sheep was cloned in 1996, scientists had managed to clone numerous other animals, including cats, cows, gaur, horses, mice, mules, pigs, rabbits and rats^[2] but had been unable to successfully clone a dog due to the problematic task of maturing a canine ovum in an artificial environment.^[2] After several failed attempts by other scientists, Woo-Suk Hwang, a professor of Seoul National University, and a team of other scientists were able to successfully create a clone using tissue from the ear of a 3-year-old Afghan hound.^{[3] [4]} 123 surrogate mothers were used to carry the embryos, of which 1,095 were implanted, the procedure resulted in only three pregnancies; one resulted in a miscarriage, the other pup was born successfully but died of pneumonia three weeks after birth, the successful clone was carried by a Labrador Retriever.^[2] From the original 1,095 embryos to the final two puppies, this placed the success rate of the project at less than two tenths of a percent.^[3] Snuppy was named as a portmanteau of the initials of the Seoul National University (SNU) and the word "puppy".^[5]

Process[link]

As the eggs in a female canine are only fertile during the estrus phase of the estrous cycle, the eggs could only be harvested during a three-week period each year. Due to complexities with removing eggs from canine ovaries the eggs had to be extracted from the oviduct, which required constant monitoring to achieve.^[6] The nucleus of each egg was replaced with the cell from the ear of the adult dog and then electrified and fused using a chemical reaction. The embryos were then transferred to the surrogate dogs. Three of the surrogate mothers became pregnant and two successfully gave birth. Snuppy, the first to be born, survived while the other died two weeks after birth.^[6] This process of cloning Snuppy took nearly three years of intensive effort.^[7]

Reaction[link]

Snuppy was named as Time Magazine's "Most Amazing Invention" of the year in 2005.^[3] Particular recognition was given to the cloning technique used in the process, which Time stated was "embodied by a history-making puppy". Despite numerous labs performing mammalian cloning, they cited that Hwang's team and Snuppy were "extraordinary".^[6][8] The experiment was criticised by Robert Klitzman, director of Columbia University's Masters in Bioethics program, who cited that the process raised the question of if humans are "just a mass of cells and biological processes?"^[6] Hwang himself criticised the process, stating that it did not bring science any closer to human cloning and the complexities, coupled with the low success rate (one in 123), did not make it ethical to clone family pets.^[2] Ian Wilmut, the scientist behind the successful cloning of Dolly the sheep, said that the successful cloning of Snuppy proved that any mammal could be cloned in the correct environments and that a global ban on human cloning needed to be quickly implemented because of this.^[2] The Kennel Club criticised the entire concept of dog cloning, on the grounds that their mission is to "To promote in every way the general improvement of dogs" and no improvement can occur if replicas are being created.^[4]

Controversy[link]

Between late 2005–2006 Hwang was accused of a series of misconducts. The first allegations related to his work prior to Snuppy; the claim that he had successfully cloned a human embryo. The charges alleged Hwang had paid for egg donations and that some of eggs came from his employees, which constitute serious breaches of the code of bioethics. It was later found that photographs he published did not depict what was suggested and that most of the stem-cell lines he claimed to have created were not clones at all.^[9] This brought serious doubts onto the validity of Snuppy, which Hwang consistently claimed was a genuine clone. Hwang hired HumanPass Inc., a Korean DNA lab to investigate Snuppy, who found that Snuppy was authentic. The findings by HumanPass were dismissed on the grounds that they were employed by Hwang, and a panel at the Seoul National University ordered their own investigation.^[10] The investigation found that, despite his fabrications in previous projects, Hwang's research related to Snuppy was accurate and Snuppy was a clone of the adult Afghan hound.^[11] As a result of his forgeries, Hwang was indicted for fraud and dismissed from the university.^[12]

Subsequent developments[link]

After Hwang Woo-Suk was dismissed from the university, veterinary professor Lee Byung-Chun took over leadership of the team behind Snuppy.^[13] In 2008, Snuppy became involved in the first known successful breeding between cloned canines, after sperm taken from Snuppy was used to artificially inseminate two cloned females, which resulted in the birth of 10 puppies.^[14] Nine of the puppies survived.^[15] The SNU team, under Lee, have gone on to successfully clone over 30 dogs and five wolves.^[16] After successfully breeding the cloned wolves, Lee claimed that the ability to breed cloned canines makes it possible for working dogs which are usually sterilised before training, such as sniffer dogs and guide dogs, to reproduce.^[17] SNU, which claims to own the patent for the process used to clone Snuppy, formed a license agreement with RNL Bio, a commercial pet cloning company. Hwang entered into a partnership with RNL Bio's competitor, BioArts International, which caused an on-going legal battle into who owns the patent rights.^[12][18] RNL completed the first commercial cloning in August 2008.^[19]

The world's first cloned sniffer dogs (all of which are named Toppy) were put to work by South Korean customs in July 2009.^[20]

References[link]

Vybz Kartel
Background information
Birth name	Adidja Palmer
Born	(1976-01-07) 7 January 1976 (age 36) Kingston, Jamaica
Origin	Portmore, Jamaica
Genres	Reggae, Dancehall, Reggae fusion
Occupations	Deejay, songwriter, entrepreneur, lyricist, producer
Years active	2000–present
Labels	Adidjaheim Records
Associated acts	Beenie Man, Aidonia, Elephant Man, Ninjaman, The Alliance, Portmore Empire, Major Lazer & Popcaan, Kano, Vanessa Bling
Website	www.vybzkartel.co.uk

Adidja Palmer (born 7 January 1976)- ^[1][2][3] better known as Vybz Kartel, is a Jamaican dancehall artist, songwriter and businessman. He has many nicknames, including: Addi, The Teacher, World Boss, Kartel, Vybz, Gaza General and Gaza Don.

Biography[link]

Adidja Palmer began his career as a teenager in 1993 with his first recording "Love Fat Woman", released on Alvin Reid's label "One Heart", using the moniker "Adi Banton", a homage to Buju Banton.^[4] Palmer was later part of the three-member group "Vybez Cartel", keeping the slightly altered name after group split up, and became a protege of Bounty Killer, for whom he claims to have written nearly 30 songs, including "Gal Clown".^[5]

Vybz Kartel rose to prominence in 2003 after a string of hits in Jamaica. The year culminated in a pre-planned on-stage clash with Ninjaman at the annual dancehall festival Sting in Kartel's hometown of Portmore. The clash turned violent when Kartel's crewmembers, as well as Kartel himself, threw punches and assaulted Ninjaman onstage.^[6] While Kartel's manager initially blamed Ninjaman for the fracas,^[6] Kartel himself quickly apologised to Ninjaman and Sting organizers for the fracas.^[7] Four days after the incident, the two artists appeared before the press to announce a settlement of their differences and to end any animosity.^[8]

He established his own label Adidjahiem/Notnice Records with his business partner and producer Ainsley "Notnice" Morris.^[9] In 2010, he released his album Pon Di Gaza 2.0 on Adidjahiem/Notnice Records in collaboration with Tads Record Inc.^[10] In Spring 2011, Vybz Kartel released an album entitled 'Kingston Story' with Brooklyn hip hop/electro producer Dre Skull.^[11]

Kartel has worked on collaborations and remixes with hip hop and R&B musicians Jay-Z, Rihanna, Missy Elliott, Busta Rhymes, M.I.A, Pharrell, Kardinal Offishall, Akon, Jim Jones, Lil Wayne and Eminem.

In 2009 he had succeeded internationally with his hit song featuring a popular female Jamaican Deejay 'Spice' - "Ramping Shop" debuting on the Billboard Top 100 Singles charts,^[12] and "Dollar Sign" being in regular rotation on urban radio stations in the US.^[13] His 2010 single "Clarks" was one of his biggest international successes, remaining in the top 3 Reggae Singles gaining the most radio plays in North America for 40 weeks.^[14] "Clarks" was also featured on the TV series So You Think You Can Dance Canada,^[15] and on a CNN segment on dancehall dance.^[16] MTV's Vice Guide to Dancehall featured Kartel at his weekly dance party, Street Vybz Thursday.^[17]

After splitting with Bounty Killer-led Alliance in 2006, Kartel founded the Portmore Empire, a group of dancehall deejays and singers from his Portmore neighborhood that he signed to his newly founded Adidjahiem/Notnice Records. Members of the group as of 2011 were: Popcaan, Shawn Storm, Sheba, Gaza Indu, Tommy Lee, Singing Maxwell, Singa Blinga, Lenny Mattic. Former members include Lisa Hype,^[18] Gaza Kim,^[19] Black Ryno,^[20] Jah Vinci, Dosa Medicine and Merital Family^[21].

Feud with Mavado[link]

Towards the end of 2006, Vybz Kartel left The Alliance. Tensions arose following Kartel's continued association with Bounty Killer's longtime enemy, Beenie Man, including Kartel attending Beenie Man's wedding to Bounty Killer's ex-girlfriend D'Angel.^[22] Due to Kartel's defection from The Alliance and his 'parring' (fraternising) with Beenie Man, a series of songs and counteraction songs ensued - the main proponents being Kartel and Mavado.

A very public feud between Vybz Kartel and former collaborator Mavado arose towards the end of 2006, stemming from Vybz' much publicized departure from the dancehall conglomerate group The Alliance. The feud resulted in numerous diss tracks released, in which each artist dissed the other and their associates over popular dancehall rhythms.^[23] In a police-overseen press conference in March 2007, both Mavado and Vybz Kartel publicly announced an end to hostilities and apologized to fans.^[24]

However, by the summer of 2008, tensions flared with a renewal of "diss tracks" from each artist, and a lyrical clash between the two at Sting 2008 left mixed views as to the "winner".^[25][26] Most of 2009 saw a continuation of the public feud, which dominated Jamaican media and, to a certain extent, Jamaican culture, with the two artists' factions, Gaza (Kartel) and Gully (Mavado), being adopted by Jamaican youth, in some cases leading to street violence.^[27][28]

On 8 December 2009, Kartel and Mavado met with Jamaican Prime Minister Bruce Golding in an attempt to end the feud, which had by that time fueled mob attacks in some of the inner-city neighborhoods of Kingston.^[29] The two had performed together on-stage the previous night in a sign of goodwill at the West Kingston Jamboree, a concert promoted by drug lord^[30] Christopher "Dudus" Coke.^[23] After the truce in December 2009, the two artists were scheduled to perform a unity concert March 2010 in Barbados, which was later cancelled by the prime minister of that country.^[31]

Business[link]

In 2008, Vybz Kartel launched his own liquor line Street Vybz Rum. He hosts a weekly dance party Street Vybz Thursday, at the Building, Kingston nightclub he manages with Street Vybz Rum business partner Corey Todd.^[32] The rum is officially distributed by Vybz Distillers Limited. The same year, he also released his own condom line, Daggering Condoms.^[33] Kartel's goal for 2011 is to release his own shoe line named Addi's, as well as his own line of "cake soap".^[34]

When his singles "Clarks", "Clarks 2 (Clarks Again)" and "Clarks 3 (Wear Weh Yuh Have)" featured the British shoe brand Clarks in 2010, its sales numbers and prices in Jamaica increased considerably.^[35]

Vybz Kartel has also hosted his own reality television show "Teacha's Pet" on CVM Jamaica broadcast channel, the first reality television show hosted by a dancehall artist in Jamaica. The premise of "Teacha's Pet" finds 20 women living in a Kingston house vying for the artist's affection; the show's lascivious content elicited condemnation of its sponsor, telecommunications company LIME. The show came to a halt with the artist's arrest on murder charges in September 2011.

Controversies[link]

Whitening[link]

Vybz Kartel's Skin before and after he bleached his skin

Kartel has come under controversy over perceived skin whitening, or "bleaching", leading him to claim to the use of "cake soap" to lighten his skin.^[36][37] The Blue Power Group, Jamaican manufacturer of the popular cake soap (or "blue soap"), has refuted claims it changes skin color.^[38] Kartel then stated the soap used to lighten his skin was his own brand, which he intends to release on the local market.^[34]

Airwave Ban[link]

In September 2011 the National Communications Network of Guyana banned Vybz Kartel from the airwaves—the first such action against a specific artist. His music contained "obscene lyrics" and brought "nothing positive" to the entertainment industry, said NCN spokesman Martin Goolsarran (Wednesday, Sept 21st) after a week of internal debate. He said NCN was reviewing the lyrics of other musicians and could ban them as well. In fact the government had no problem with Kartel, its Tourism Ministry inviting him to an August music festival, but he angered it and Guyanese promoters when he failed to show up.^[39]

Murder charge[link]

Vybz Kartel being arrested in October 2011

On 29 September 2011, Kartel was arrested by police. Jamaica's Major Investigation Taskforce (MIT) charged him with murder, conspiracy to murder and illegal possession of a firearm. The deceased was Barrington 'Bossie' Burton, a 27-year-old businessman and music promoter based in the Kingston suburb of Portmore. They first visited Kingston's Norbrook community where the DJ resides, then went to a property on Swallowfield Avenue in Kingston's Havendale area. That residence was the scene of a fire several weeks ago; a scorched computer hard-drive and several boxes were removed. They then drove to Portmore to a home purportedly owned by Kartel's mother, where a number of items were similarly confiscated. Kartel was detained for the weekend in relation to a partially burned, decomposing body found inside the Swallowfield Avenue home.^[40]

Kartel was granted bail for the Burton murder 23 March 2012 for JD$3,000,000, but currently remains jailed in connection on a second murder, of one Clive 'Lizzard' Williams.^[41]

Discography[link]

Albums[link]

• 2003: Up 2 Di Time
• 2004: More Up 2 Di Time
• 2005: J.M.T.
• 2009: Most Wanted
• 2010: Pon di Gaza 2.0
• 2011: Kingston Story

Singles[link]

Guest appearances[link]

Awards[link]

Kartel has had several collaborations with international hip hop and pop stars. He has released two albums for the UK/US based label Greensleeves Records. He was also nominated for the Source,^[43] VIBE and UK MOBO awards, although his 2004 UK MOBO award nomination was withdrawn amidst controversy over homophobic content of his lyrics.^[44]

• 2003
  • Stone Love's 30th Anniversary
    • DJ of the Year 2005

• 2008
  • CUMA (Caribbean Urban Music Awards)

• 2009
  • EME Awards^[45]
    • Male DJ of the Year
    • Lyricist/Songwriter of the Year
    • Song of the Year (Romping Shop ft. Spice)

• 2010
  • EME Awards^[46]

References[link]