company name | Wyeth |
---|---|
company logo | |
company type | Subsidiary |
foundation | (1860) Philadelphia, Pennsylvania, U.S. |
location | Madison, New Jersey, United States |
key people | Bernard J. Poussot, CEO, President and Vice Chairman of WyethRobert Essner, ChairmanJoseph Mahady, President, Global Business, Wyeth PharmaceuticalsJohn Wyeth, Founder |
industry | Pharmaceuticals, Healthcare |
products | Premarin,Effexor,Enbrel,(See more products.) |
parent | Pfizer |
revenue | US$ 22.40 billion (2008) |
net income | US$ 4.616 billion (2008) |
market cap | US$ 41 billion (Oct. 2008) |
num employees | 49,732 (2005) |
homepage | www.wyeth.com }} |
Wyeth, formerly one of the companies owned by American Home Products Corporation (AHP), was a pharmaceutical company. The company was based in Madison, New Jersey, USA. They were known for manufacturing the over-the-counter (OTC) drugs Robitussin and the analgesic Advil (ibuprofen), as well as the prescription drugs Premarin and Effexor, which both boast over US$3 billion in sales annually.
On January 23, 2009 ''The Wall Street Journal'' reported that Pfizer was in talks to buy Wyeth at a cost of US$68 billion. On January 25, Pfizer agreed to the purchase, a deal financed with cash, shares and loans. The deal was completed on October 15, 2009.
In 1872, Henry Bower, an employee of Wyeth, developed one of the first rotary compressed tablet machines in the United States. This enabled the mass production of medicines with unprecedented precision and speed. It was successful, and the Wyeth brothers won multiple awards at the Centennial Exhibition. In 1883, Wyeth opened its first international facility in Montreal, Canada and began vaccine production. Six years later a fire destroyed the brothers' original Walnut Street store, and they sold the retail business and focused on mass production.
In 1935, Alvin G. Brush, a Certified Public Accountant, became CEO of the organization and served for 30 years. Under Brush's leadership, 34 new companies were acquired in 15 years, including Chef Boyardee and the ''S.M.A. Corporation'', a pharmaceutical firm specializing in infant formulas. Wyeth also made its first licensing deal, acquiring an antibiotic for arthritis vaccine research.
In 1941, the US entered World War II, and Wyeth shipped typical wartime drugs such as sulfa bacteriostatics, blood plasma, typhus vaccine, quinine, and atabrine tablets. Wyeth was later rewarded for its contribution to the war effort. During this time, Wyeth launched its penicillin research facility with G. Raymond Rettew.
In 1943, Wyeth purchased ''G. Washington Coffee Refining Company'', an instant coffee company created by George Washington.
In 1943, Wyeth merged with ''Ayerst, McKenna and Harrison, Ltd.'' of Canada. With this merger came Premarin, the world's first conjugated estrogen medicine, which was a flagship product for Wyeth until 2002, when preliminary results from the Women's Health Initiative linked it to a number of negative effects, including increased risk for breast cancer. Sales subsequently fell off worldwide.
Wyeth was one of 22 companies selected by the government in 1944 to manufacture penicillin for the military, and later for the general public.
In 1945, Wyeth acquired the Fort Dodge Serum Company, entering the animal health field.
Wyeth became a leading US vaccine producer after supplying polio vaccine for Salk trials. The corporate headquarters were moved to Radnor, Pennsylvania, where they remained until 2003. William F. Laporte became the Chairman and President of AHP in 1965, and served until 1981.
The World Health Organization initiated the Global Smallpox Eradication Program in 1967, and approached Wyeth to develop a better injection system for smallpox vaccines which could be used in the field. Wyeth waived patent royalties on its innovative bifurcated needle, aiding in the delivery of over 200 million smallpox vaccines per year.
John R. Stafford became CEO and Chairman in 1986. He completed the divestiture of non-core businesses such as household products, foods, and candy. Wyeth and Ayerst merged to form Wyeth-Ayerst Laboratories, thus strengthening and consolidating Wyeth's pharmaceutical operations.
In the late 1980s, Wyeth acquired the animal health businesses of Bristol-Myers and Parke-Davis. Wyeth also acquired A.H. Robins, makers of Robitussin, ChapStick, Dimetapp, and the Dalkon Shield.
Premarin becomes the #1 prescribed drug in the US in 1993. Effexor (venlafaxine HCl), the first serotonin-norepinephrine reuptake inhibitor (SNRI), is introduced for the treatment of clinical depression and is later indicated for generalized anxiety disorder and social anxiety disorder.
In 1993, Wyeth founded the ''Women's Health Research Institute'', the only institute in the pharmaceutical industry entirely dedicated to research in women's health. The Institute conducts trials in menopausal issues, endometriosis, contraception, and more.
In 1994, Wyeth acquired American Cyanamid and its subsidiary Lederle Laboratories. This acquisition brought the Lederle Praxis vaccines, new research and development capacity, and Centrum, the leading US multivitamin. Wyeth's sales topped US$13 billion in 1995; two years later, Premarin became the company's first brand to reach US$1 billion in sales.
In 1995, Wyeth acquired the animal health division of Solvay, which was folded into Fort Dodge Animal Health. The acquisition gave Fort Dodge Animal Health strong market presence in Europe and Asia as well as expanding its product portfolio to include swine and poultry vaccines.
In 1996, American Home Products spun off its food unit as International Home Foods. International Home Foods was purchased by ConAgra Foods in 2000.
In 1997, Wyeth's controversial diet drug fenfluramine was taken off the market by the U.S. Food and Drug Administration (FDA) after several reports of deaths and other health problems associated with the drug combination known as fen-phen occurred.
In 1998, American Home Products was left at the altar by British pharma powerhouse SmithKline Beecham, who pulled the plug on the estimated $70 billion merger. The deal was reportedly killed in response to British regulators who feared losing jobs to a proposed US headquarters location. (SmithKline Beecham merged with fellow Brit Glaxo Wellcome in 1999 to form the world's leading drug company.) This was the start of a three-year losing streak in the mergers and acquisitions game for AHP.
In 1999, another American Home Products merger fell through, this time a proposed $34 billion merger-of-equals with chemical and biotech manufacturer Monsanto Company. Though the companies issued a combined statement saying the breakup was mutual "because (the deal) was not in the best interests of shareholders," rumors circulated that AHP had canceled the deal due to issues in the soon-to-be-combined boardroom. (Monsanto announced in December 1999 that it would merge with Pharmacia & Upjohn instead; the new conglomerate eventually unloaded Monsanto again, before being bought themselves by Pfizer in 2003.)
Robert Essner, the company's former CEO, was appointed in 2001. On September 27, 2007, the Wyeth Board of Directors elected Bernard Poussot President and Chief Executive Officer effective on January 1, 2008.
In 2002, American Home Products changed its name to Wyeth, having spun off unrelated businesses in order to focus on pharmaceuticals.
As part of the Women's Health Initiative sponsored by the National Institutes of Health, a large-scale clinical trial for Hormone Replacement Therapy showed that long-term use of progestin and estrogen may increase the risk of strokes, heart attacks, blood clots, and breast cancer. Following these results, Wyeth experienced a significant decline in its sales of Premarin, Prempro (conjugated equine estrogens) and related hormones, from over $2 billion in 2002 to just over $1 billion in 2006. The results from the study were significant enough that Wyeth terminated the trials early due to a fear that their participants may be at risk.
Wyeth, as a corporation, filed a 'citizens complaint' with the United States FDA on October 16, 2005, requesting that the US FDA take action against pharmacies who compound, manufacture, or sell unlicensed Bioidentical hormone replacement therapy (BHRT) drugs to their patients. Specifically, Wyeth asserted that the BHRT drugs are not licensed by the FDA according to section 505 of the Food, Drug and Cosmetic Act, misbranded and adulterated per sections 501 and 502 of 21 U.S.C. (paragraphs 351, 352, and 355). Drug manufacturers are required to demonstrate through clinical trials that marketed drugs are safe and efficacious, a process that BHRT drugs have not undergone. If honored, the request would require the same safety and efficacy data for those primarily engaged in alternative medicine.
The European Commissioner for Health and Consumer Protection blamed the presence of illegal steroids in the food supply on "fraudulent exchange and disposal of pharmaceutical waste". A Wyeth factory disposing of the byproducts from synthetic progesterone manufacture was the source of the contamination.
In 2003 Wyeth reportedly contributed funds to a not-for-profit support group, The Meningitis Centre, which lobbied the Australian Government to introduce universal immunisation against pneumococcal disease. Wyeth produced the only pneumococcal vaccine approved for young children in Australia.
In 2008 the CFO and CEO were replaced.
During June 2009, an Arkansas federal judge granted public access to evidence that Wyeth Pharmaceuticals “ghostwrote� medical articles regarding its hormone therapy drug Prempro. Along with ''The New York Times'', PLoS Medicine, represented by the law firm Public Justice, had sought to intervene in a court case of women bringing an action in relation to Prempro and other hormone therapy drugs, in order to unseal papers that allegedly showed that Wyeth failed to disclose its role in preparing medical journal articles promoting Prempro and in recruiting academic authors to put their names on the articles for publication—that is that they practised ghost writing.
On October 15, 2009 Pfizer signed the final acquisition papers making Wyeth a wholly owned subsidiary of Pfizer, thus completing the US$68 billion dollar deal.
Innovative Fort Dodge products include West Nile-Innovator, Duramune Adult, CYDECTIN Pour-on, the Pyramid vaccine line, Quest Gel, and EtoGesic Tablets.
Category:Pfizer Category:Companies established in 1860 Category:Multinational companies Category:Pharmaceutical companies of the United States Category:Companies based in Morris County, New Jersey Category:Companies based in Rockland County, New York Category:Madison, New Jersey Category:Vaccine producers
de:Wyeth es:Wyeth fr:Wyeth ja:ワイス (ä¼?æ¥) ro:Wyeth ru:Wyeth sv:Wyeth th:ไวเà¸à¸• tr:Wyeth zh:æƒ æ°?This text is licensed under the Creative Commons CC-BY-SA License. This text was originally published on Wikipedia and was developed by the Wikipedia community.
name | Andrew Wyeth |
---|---|
birth date | July 12, 1917 |
birth place | Chadds Ford, Pennsylvania,United States |
death date | January 16, 2009 |
death place | Chadds Ford, Pennsylvania,United States |
resting place | Hathorn Cemetery Cushing, Maine |
occupation | Realist painter }} |
Andrew Newell Wyeth ( ; 1917–2009) was a visual artist, primarily a realist painter, working predominantly in a regionalist style. He was one of the best-known U.S. artists of the middle 20th century.
In his art, Wyeth's favorite subjects were the land and people around him, both in his hometown of Chadds Ford, Pennsylvania, and at his summer home in Cushing, Maine. One of the most well-known images in 20th-century American art is his painting, ''Christina's World'', currently in the collection of the Museum of Modern Art in New York City.
Andrew was home-tutored because of his frail health. Like his father, the young Wyeth read and appreciated the poetry of Robert Frost and writings of Henry Thoreau and studied their relationships with nature. Music and movies also heightened his artistic sensitivity. One major influence, discussed at length by Wyeth himself was King Vidor's The Big Parade. He claims to have seen the film which depicted family dynamics similar to his own, "a hundred-and-eighty-times" and believes it had the greatest influence on his work. The film's director Vidor later made a documentary, ''Metaphor'' where he and Wyeth discuss the influence of the film on his paintings, including ''Winter 1946'', ''Snow Flurries'', ''Portrait of Ralph Kline'' and ''Afternoon Flight of a Boy up a Tree.''
Wyeth's father was the only teacher that he had. Due to being schooled at home, he led both a sheltered life and one that was "obsessively focused". Wyeth recalled of that time: "Pa kept me almost in a jail, just kept me to himself in my own world, and he wouldn’t let anyone in on it. I was almost made to stay in [ Robin Hood's ] Sherwood Forest with Maid Marion and the rebels."
In the 1920s Wyeth's father had become a celebrity and the family often had celebrities as guests, such as F. Scott Fitzgerald and Mary Pickford. The home bustled with creative activity and competition. N.C. and Carolyn's five children were all talented. Henriette Wyeth Hurd, the eldest, became a well-known painter of portraits and still lifes. Carolyn, the second child, was also a painter. Nathaniel Wyeth the third child a successful inventor. Ann, was a musician at a young age, then became a composer as an adult. Andrew was the youngest child.
With his father’s guidance, he mastered figure study and watercolor, and later learned egg tempera from his brother-in-law Peter Hurd. He studied art history on his own, admiring many masters of Renaissance and American painting, especially Winslow Homer.
N.C. also fostered an inner self-confidence to follow one's own talents without thought of how the work is received. N.C. wrote in a letter to Wyeth in 1944:
"The great men [ Thoreau, Goethe, Emerson, Tolstoy] forever radiate a sharp sense of that profound requirement of an artist, to fully understand that ''consequences'' of what he creates are unimportant. Let the motive for action be in the action itself and not in the event. I know from my own experience that when I create with any degree of strength and beauty I have no thought of consequences. Anyone who creates for ''effect'' — to score a hit — does not know what he is missing!"
In the same letter N.C. correlates being a great man with being a great painter: To be a great artist, he described, requires emotional depth, an openness, to look beyond self to the subject, and passion. A great painting then is one that enriches and broadens one's perspective.
In October 1945, his father and his three-year-old nephew, Newell Convers Wyeth II (b. 1941), were killed when their car stalled on railroad tracks near their home and was struck by a train. Wyeth referred to his father's death as a formative emotional event in his artistic career, in addition to being a personal tragedy. Shortly afterwards, Wyeth's art consolidated into his mature and enduring style.
Their first child Nicholas was born in 1943, followed by James ("Jamie") three years later. Wyeth painted portraits of both children. His son, Jamie Wyeth, followed his father's and grandfather's footsteps, becoming the third generation of Wyeth artists.
Wyeth was a visual artist, primarily classified as a realist painter, like Winslow Homer or Eakins. In a "Life Magazine" article in 1965, Wyeth said that although he was thought of as a realist, he thought of himself as an abstractionist: "My people, my objects breathe in a different way: there’s another core — an excitement that’s definitely abstract. My God, when you really begin to peer into something, a simple object, and realize the profound meaning of that thing — if you have an emotion about it, there’s no end."
He worked predominantly in a regionalist style. In his art, Wyeth's favorite subjects were the land and people around him, both in his hometown of Chadds Ford, Pennsylvania, and at his summer home in Cushing, Maine.
Dividing his time between Pennsylvania and Maine, Wyeth maintained a realist painting style for over fifty years. He gravitated to several identifiable landscape subjects and models. His solitary walks were the primary means of inspiration for his landscapes. He developed an extraordinary intimacy with the land and sea and strove for a spiritual understanding based on history and unspoken emotion. He typically created dozens of studies on a subject in pencil or loosely brushed watercolor before executing a finished painting, either in watercolor, drybrush (a watercolor style in which the water is squeezed from the brush), or egg tempera.
The Olson house has been preserved, renovated to match its appearance in ''Christina's World''. It is open to the public as a part of the Farnsworth Art Museum.
Wyeth created nearly 300 drawings, watercolor and tempera paintings, mostly in a palette of gold, charcoal, brown and blue. Because of Wyeth's popularity, the property was designated a National Historic Landmark in June 2011.
A short distance from the house near the water is the Hathorn family cemetery which includes the burial place of Christina Olson, her brother Alvaro and Andrew Wyeth. In a 2007 interview, Wyeth's granddaughter, Victoria , revealed he wanted to be buried near Christina and the spot where he painted ''Christina's World''.
The Kuerners' farm is available to tour through the Brandywine River Museum, as is the nearby N. C. Wyeth House and Studio; in 2011, the farm was declared a National Historic Landmark, based on its association with Wyeth.
In 1986, millionaire Leonard E.B. Andrews (1925–2009) purchased almost the entire collection, preserving it intact. Wyeth had already given a few Helga paintings to friends, including the famous ''Lovers'', which had been given as a gift to Wyeth's wife.
The works were exhibited at the National Gallery of Art in 1987 and in a nationwide tour.
In a 2007 Interview, when Wyeth was asked if Helga was going to be at his 90th birthday party, he said "Yeah, certainly. Oh, absolutely" and went on to say "She's part of the family now, I know it shocks everyone. That's what I love about it. It really shocks 'em."
Admirers of Wyeth's art believe that his paintings, in addition to their pictorial formal beauty, contain strong emotional currents, symbolic content, and underlying abstraction. Most observers of his art agree that he is skilled at handling the media of egg tempera (which uses egg yolk as its medium) and watercolor. Wyeth avoided using traditional oil paints. His use of light and shadow let the subjects illuminate the canvas. His paintings and titles suggest sound, as is implied in many paintings, including ''Distant Thunder'' (1961) and ''Spring Fed'' (1967). ''Christina's World'' became an iconic image, a status unmet to even the best paintings, "that registers as an emotional and cultural reference point in the minds of millions."
Wyeth created work in sharp contrast to abstraction, which gained currency in American art and critical thinking in the middle of the 20th century.
Museum exhibitions of Wyeth's paintings have set attendance records, but many art critics have evaluated his work less favorably. Peter Schjeldahl, art critic for ''The Village Voice'', derided his paintings as "Formulaic stuff, not very effective even as illustrational 'realism.' " Some found Wyeth's art of rural subject matter tired and oversweet.
Bo Bartlett, a close friend and student of Wyeth, commented on his teacher's view of this criticism during an interview with Brian Sherwin in 2008: "People only make you swerve. I won’t show anybody anything I’m working on. If they hate it, it’s a bad thing, and if they like it, it’s a bad thing. An artist has to be ingrown to be any good." N.C. advised Wyeth to work from one's own perspective and imagination; to work for "effect" means the artist is not fully exploring their artistic abilities and as a result the artist will not realize their potential.
He also received numerous honorary degrees.
Category:1917 births Category:2009 deaths Category:American painters Category:Artists from Pennsylvania Category:Congressional Gold Medal recipients Category:Members of the American Academy of Arts and Letters Category:Modern painters Category:United States National Medal of Arts recipients Category:Wyeth family
ar:أندرو واÙ?Ø« cs:Andrew Wyeth de:Andrew Wyeth es:Andrew Wyeth fa:اندرو وایت fr:Andrew Wyeth haw:Andrew Wyeth it:Andrew Wyeth la:Andreas Wyeth lb:Andrew Wyeth hu:Andrew Wyeth mi:Andrew Wyeth nl:Andrew Wyeth ja:アンドリュー・ワイエス nn:Andrew Wyeth pt:Andrew Wyeth ru:Уайет, ÐндрÑ? se:Andrew Wyeth fi:Andrew Wyeth sv:Andrew Wyeth uk:ЕндрÑ? Ваєт zh:安德é¯Â·é?æ–¯This text is licensed under the Creative Commons CC-BY-SA License. This text was originally published on Wikipedia and was developed by the Wikipedia community.
Katya Wyeth appeared in the films ''Hands of the Ripper'' (1971) and ''Burke and Hare'' (1972). Her best-remembered role is probably as 'Countess Mircalla' in the 'Hammer horror' film ''Twins of Evil'' (1971), where she appeared alongside Peter Cushing.
Katya Wyeth was the actress famously seen frolicking with Alex (Malcolm MacDowell) in the 'Ascot fantasy' sequence that closes ''A Clockwork Orange'' (1971).
This text is licensed under the Creative Commons CC-BY-SA License. This text was originally published on Wikipedia and was developed by the Wikipedia community.
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