The American Journal of Medicine

The American Journal of Medicine is a peer-reviewed medical journal and the official journal of the Alliance for Academic Internal Medicine. It was established in 1946. The journal is published monthly by Elsevier under its Excerpta Medica imprint. It is also known as "the green journal".

Joseph S. Alpert (University of Arizona College of Medicine) became editor-in-chief of the journal in 2004. At that time, the editorial office moved to Tucson, Arizona.

Abstracting and indexing

The journal is abstracted and indexed in:

References

External links

Proposed top-level domain

The Domain Name System of the Internet consists of a set of top-level domains which constitute the root domain of the hierarchical name space and database. In the growth of the Internet, it became desirable to expand the set of initially six generic top-level domains in 1984. As a result new top-level domain names have been proposed for implementation by ICANN. Such proposals included a variety of models ranging from adoption of policies for unrestricted gTLDs that could be registered by anyone for any purpose, to chartered gTLDs for specialized uses by specialized organizations. In October 2000, ICANN published a list of proposals for top-level domain strings it had received.

Geographic proposals

MED28

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.

Function

Subunit Med28 of the Mediator may function as a scaffolding protein within Mediator by maintaining the stability of a submodule within the head module, and components of this submodule act together in a gene-regulatory programme to suppress smooth muscle cell differentiation. Thus, mammalian Mediator subunit Med28 functions as a repressor of smooth muscle-cell differentiation, which could have implications for disorders associated with abnormalities in smooth muscle cell growth and differentiation, including atherosclerosis, asthma, hypertension, and smooth muscle tumours.

Interactions

MED28 has been shown to interact with Merlin,Grb2 and MED26.

See also

References

This article incorporates text from the public domain Pfam and InterPro IPR021640

Further reading

MED6

Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.

Protein family

This family of proteins represent the transcriptional mediator protein subunit 6 that is required for activation of many RNA polymerase II promoters and which are conserved from yeast to humans.

Interactions

MED6 has been shown to interact with:

References

Further reading

External links

This article incorporates text from the public domain Pfam and InterPro IPR007018