State Route 60 is a state highway in the U.S. state of California. It runs from Interstate 10 near the Los Angeles River in Los Angeles east to I-10 in Riverside County, with overlaps at State Route 57 and Interstate 215.

This route is part of the California Freeway and Expressway System.

Route 60 serves the cities and communities on the eastern side of the Los Angeles metropolitan area and runs along the south side of the San Gabriel Valley. The west terminus of the freeway is at the East Los Angeles Interchange complex. The east terminus is at the junction with the San Bernardino Freeway, Interstate 10 (I-10) in Beaumont. The freeway is known as the Pomona Freeway west of its junction with State Route 91 and Interstate 215 in Riverside. East of this interchange the freeway is known as the Moreno Valley Freeway until its terminus at its junction with Interstate 10. The freeway shares the alignment of the Orange Freeway, State Route 57 for some 2 miles (3.2 km) in Diamond Bar and also shares the alignment of Interstate 215 for about 5 miles (8.0 km) in Riverside. The route takes its number from former U.S. Route 60.

Moreno Valley is a city located in Riverside County, California.

A relatively young city, its rapid growth in the 1980s and the first decade of the 21st century made it second-largest city in Riverside County by population, and one of the Inland Empire's population centers. As of the 2010 census, the city's population was 193,365. Neighboring Riverside, California is the county seat and largest city in the county and the two cities are closely tied.

Located just north of Lake Perris, Moreno Valley shares March Joint Air Reserve Base with both Riverside, California and the city of Perris.

Moreno Valley was originally inhabited by hunter-gatherer Native Americans of the Shoshone tribe. The first Europeans were Spanish scouts, sent from Mexico to explore the area. These Spanish scouts blazed a number of trails in the area, including the Anza Trail, which runs through the Edgemont area of present-day Moreno Valley. The relatively dry portion of the city was largely ignored by these earliest settlers.