Nacogdoches ( /ˌnækəˈdoʊtʃɨs/ NAK-ə-DOH-chəs) is a city in Nacogdoches County, Texas, in the United States. The 2010 census recorded the city's population to be 32,996. It is the county seat of Nacogdoches County and is situated in East Texas. Nacogdoches is a sister city of Natchitoches, Louisiana.

Nacogdoches is the home of Stephen F. Austin State University and of the Association for Business Communication.

The town made international headlines in February 2003, after receiving much of the Space Shuttle Columbia disaster debris.

Nacogdoches is located at 31°36′32″N 94°39′3″W / 31.60889°N 94.65083°W / 31.60889; -94.65083 (31.608855, -94.650862). Its location is approximately 140 miles (225 km) NNE of Houston, 180 miles (290 km) SE of Dallas and 90 miles (145 km) SW of Shreveport.

According to the United States Census Bureau, the city has a total area of 25.3 square miles (66 km²), of which, 25.2 square miles (65 km²) of it is land and 0.1 square miles (0.26 km²) of it (0.24%) is water. The city center is located just to the north of the fork of two creeks, the LaNana and Banita.

Texas (ⁱ/ˈtɛksəs/) (Alibamu: Teksi ) is the second most populous and the second most extensive of the 50 United States, and the most extensive state of the 48 contiguous United States. The name, based on the Caddo word "Tejas" meaning "friends" or "allies", was applied by the Spanish to the Caddo themselves and to the region of their settlement in East Texas. Located in the South Central United States, Texas shares an international border with the Mexican states of Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the south, and borders the US states of New Mexico to the west, Oklahoma to the north, Arkansas to the northeast, and Louisiana to the east. Texas has an area of 268,820 square miles (696,200 km²), and a growing population of 25.7 million residents.

During the Spanish colonial rule, the area was officially known as the Nuevo Reino de Filipinas: La Provincia de Texas. Antonio Margil de Jesús was known to be the first person to use the name in a letter to the Viceroy of Mexico in July 20, 1716. The name was not popularly used in daily speech but often appeared in legal documents until the end of the 1800s.