Name	Acquired immunodeficiency syndrome (AIDS)
Caption	The red ribbon is a symbol for solidarity with HIV-positive people and those living with AIDS.
Width	120
Diseasesdb	5938
Icd10
Icd9
Medlineplus	000594
Emedicinesubj	emerg
Emedicinetopic	253
Meshid	D000163

{| style="float: right; clear:right; margin: 0 0 0.5em 1em; padding: 0.5em; background: #fffff4; border: 1px solid #ddb; width: 250px; font-size:90%;" |- |List of abbreviations used in this article AIDS: Acquired immune deficiency syndrome HIV: Human immunodeficiency virus CD4+: CD4+ T helper cells CCR5: Chemokine (C-C motif) receptor 5 CDC: Centers for Disease Control and Prevention WHO: World Health Organization PCP: Pneumocystis pneumonia TB: Tuberculosis MTCT: Mother-to-child transmission HAART: Highly active antiretroviral therapy STI/STD: Sexually transmitted infection/disease |} Acquired immune deficiency syndrome or acquired immunodeficiency syndrome (AIDS) is a disease of the human immune system caused by the human immunodeficiency virus (HIV). In 2007, UNAIDS estimated: 33.2 million people worldwide had AIDS that year; AIDS killed an 2.1 million people in the course of that year, including 330,000 children, and 76% of those deaths occurred in sub-Saharan Africa. According to UNAIDS 2009 report, worldwide some 60 million people have been infected, with some 25 million deaths, and 14 million orphaned children in southern Africa alone since the epidemic began. The risk of infection is influenced by the viral load of the mother at birth, with the higher the viral load, the higher the risk. Breastfeeding also increases the risk of transmission by about 4 %.

The most prominent effect of HIV is its T-helper cell suppression and lysis. The cell is simply killed off or deranged to the point of being function-less (they do not respond to foreign antigens). The infected B-cells can not produce enough antibodies either. Thus the immune system collapses leading to the familiar AIDS complications, like infections and neoplasms (vide supra).

Infection of the cells of the CNS cause acute aseptic meningitis, subacute encephalitis, vacuolar myelopathy and peripheral neuropathy. Later it leads to even AIDS dementia complex.

The CD₄-gp120 interaction (see above) is also permissive to other viruses like Cytomegalovirus, Hepatitis virus, Herpes simplex virus, etc. These viruses lead to further cell damage i.e. cytopathy.

Molecular basis

''For details, see:

Structure and genome of HIV

HIV replication cycle

HIV tropism''

Diagnosis

The diagnosis of AIDS in a person infected with HIV is based on the presence of certain signs or symptoms. Since June 5, 1981, many definitions have been developed for epidemiological surveillance such as the Bangui definition and the 1994 expanded World Health Organization AIDS case definition. However, clinical staging of patients was not an intended use for these systems as they are neither sensitive, nor specific. In developing countries, the World Health Organization staging system for HIV infection and disease, using clinical and laboratory data, is used and in developed countries, the Centers for Disease Control (CDC) Classification System is used.

WHO disease staging system

In 1990, the World Health Organization (WHO) grouped these infections and conditions together by introducing a staging system for patients infected with HIV-1. Therefore, donor blood and blood products used in medicine and medical research are screened for HIV.

HIV tests are usually performed on venous blood. Many laboratories use fourth generation screening tests which detect anti-HIV antibody (IgG and IgM) and the HIV p24 antigen. The detection of HIV antibody or antigen in a patient previously known to be negative is evidence of HIV infection. Individuals whose first specimen indicates evidence of HIV infection will have a repeat test on a second blood sample to confirm the results.

The window period (the time between initial infection and the development of detectable antibodies against the infection) can vary since it can take 3–6 months to seroconvert and to test positive. Detection of the virus using polymerase chain reaction (PCR) during the window period is possible, and evidence suggests that an infection may often be detected earlier than when using a fourth generation EIA screening test.

Positive results obtained by PCR are confirmed by antibody tests.of HIV by exposure route (US only) per 10,000 exposuresto an infected source |- ! style="text-align:left"| Blood Transfusion | 9,000 |- ! style="text-align:left"| Receptive penile-vaginal intercourse^* | 10 |- ! style="text-align:left"| Receptive oral intercourse^*§ | 1 |- ! style="text-align:left"| Insertive oral intercourse^*§ | 0.5 |- style="background:#efefef;" ! colspan=5 style="border-right:0;"| ^* assuming no condom use ^§ source refers to oral intercourseperformed on a man |} The three main transmission routes of HIV are sexual contact, exposure to infected body fluids or tissues, and from mother to fetus or child during perinatal period. It is possible to find HIV in the saliva, tears, and urine of infected individuals, but there are no recorded cases of infection by these secretions, and the risk of infection is negligible. Current optimal HAART options consist of combinations (or "cocktails") consisting of at least three drugs belonging to at least two types, or "classes," of antiretroviral agents.

Typical regimens consist of two nucleoside analogue reverse transcriptase inhibitors (NARTIs or NRTIs) plus either a protease inhibitor or a non-nucleoside reverse transcriptase inhibitor (NNRTI). Because HIV disease progression in children is more rapid than in adults, and laboratory parameters are less predictive of risk for disease progression, particularly for young infants, treatment recommendations are more aggressive for children than for adults. HAART is thought to increase survival time by between 4 and 12 years. A large Tanzanian trial in immunologically and nutritionally compromised pregnant and lactating women showed a number of benefits to daily multivitamin supplementation for both mothers and children.

Prognosis

Without treatment, the net median survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype, and the median survival rate after diagnosis of AIDS in resource-limited settings where treatment is not available ranges between 6 and 19 months, depending on the study. Most patients die from opportunistic infections or malignancies associated with the progressive failure of the immune system. health care and co-infections, as well as which particular strain of the virus is involved. Despite recent, improved access to antiretroviral treatment and care in many regions of the world, the AIDS pandemic claimed an estimated 2.1 million (range 1.9–2.4 million) lives in 2007 of which an estimated 330,000 were children under 15 years.

Sub-Saharan Africa remains by far the worst affected region. In 2007 it contained an estimated 68% of all people living with AIDS and 76% of all AIDS deaths, with 1.7 million new infections bringing the number of people living with HIV to 22.5 million, and with 11.4 million AIDS orphans living in the region. Unlike other regions, most people living with HIV in sub-Saharan Africa in 2007 (61%) were women. Adult prevalence in 2007 was an estimated 5.0%, and AIDS continued to be the single largest cause of mortality in this region.

South Africa has the largest population of HIV patients in the world, followed by Nigeria and India. India has an estimated 2.5 million infections and an estimated adult prevalence of 0.36%. Life expectancy has fallen dramatically in the worst-affected countries; for example, in 2006 it was estimated that it had dropped from 65 to 35 years in Botswana. They also used Kaposi's Sarcoma and Opportunistic Infections, the name by which a task force had been set up in 1981. the term GRID became misleading and AIDS was introduced at a meeting in July 1982. A recent study states that a strain of HIV-1 probably moved from Africa to Haiti and then entered the United States around 1969. Courtesy AIDS stigma—stigmatization of people connected to the issue of HIV/AIDS or HIV- positive people.

Economic impact

HIV and AIDS affects economic growth by reducing the availability of human capital.

On the level of the household, AIDS results in both the loss of income and increased spending on healthcare by the household. The income effects of this lead to spending reduction as well as a substitution effect away from education and towards healthcare and funeral spending. A study in Côte d'Ivoire showed that households with an HIV/AIDS patient spent twice as much on medical expenses as other households.

See also

Discovery and development of CCR5 receptor antagonists

FightAIDS@Home

HIV

HIV/AIDS Bureau (in the US)

AIDS vaccine

Nutrition and HIV/AIDS

Origin of AIDS

Notes and references

Further reading

Bhargava, Alok, and Booysen, F. (2010). Healthcare infrastructure and emotional support are predictors of CD4 cell counts and quality of life indices of patients on antiretroviral treatment in Free State Province, South Africa. AIDS Care, 22, 1-9.

External links

AIDSinfo – HIV/AIDS Treatment Information, U.S. Department of Health and Human Services

UNAIDS: The Joint United Nations Programme on HIV/AIDS

Portal to all Federal HIV/AIDS information – Office of HIV/AIDS Policy

AIDS: History of a Plague - slideshow by Life magazine

Category:Acronyms Category:AIDS origin hypotheses Category:HIV/AIDS Category:Immune system disorders Category:Immunodeficiency Category:Infectious diseases Category:Health disasters Category:Microbiology Category:Pandemics Category:Sexually transmitted diseases and infections Category:Syndromes Category:Viral diseases Category:Virology

Name	George Mason
Birth name	George Mason
Birth date	December 11, 1725
Birth place	Fairfax County, Colony of Virginia
Death date	October 07, 1792
Death place	Gunston Hall, Fairfax County, Virginia
Death cause	natural causes
Resting place coordinates
Residence	Gunston Hall, Fairfax County, Virginia
Nationality	British, American
Ethnicity	English American
Citizenship	Kingdom of Great BritainUnited States
Occupation	patriot, statesman, and delegate from Virginia to the U.S. Constitutional Convention
Religion	Anglican, Episcopalian
Spouse	Ann EilbeckSarah Brent
Children	George Mason VAnn Eilbeck Mason JohnsonWilliam MasonWilliam MasonThomson MasonSarah Eilbeck Mason McCartyMary Thomson Mason CookeJohn MasonElizabeth Mason ThorntonThomas MasonJames MasonRichard Mason
Parents	George Mason IIIAnn Stevens Thomson

George Mason IV (December 11, 1725 – October 7, 1792) was an American patriot, statesman, and a delegate from Virginia to the U.S. Constitutional Convention. Along with James Madison, he is called the "Father of the Bill of Rights."

An important issue for him in the convention was the Bill of Rights. He did not want the United States to be like England. He foresaw sectional strife and feared the power of government. Mason ostensibly balanced his anti-slavery argument that importation should stop, with a pro-slavery argument that the draft Constitution should protect slavery from being taxed out of existence; however, the latter argument had already been incorporated into the Constitution according to James Madison.

Death and remembrance

George Mason died peacefully at his home, Gunston Hall, on October 7, 1792. Gunston Hall, located in Mason Neck, Virginia, is now a museum and tourist attraction. The George Mason Memorial in West Potomac Park, Washington, D.C., near the Thomas Jefferson Memorial, was dedicated on April 9, 2002. The George Mason Memorial Bridge, one of five that make up the 14th Street Bridge, connects Washington, DC, to Virginia. George Mason Elementary School in Alexandria, Virginia, George Mason High School in Falls Church, Virginia and George Mason University in Fairfax, Virginia, are named in his honor, as are Mason County, Kentucky, Mason County, West Virginia and Mason County, Illinois. He was honored by the United States Postal Service with an 18¢ Great Americans series postage stamp.

References

Bibliography

External links

George Mason biography

Gunston Hall Home Page

Amazing Mason by John J. Miller

Website of George Mason University

George Mason University Study Abroad- Center for Global Education

MasonStudents - GMU's Student Run Discussion Forum

Category:1725 births Category:1792 deaths Category:18th-century American Episcopalians Category:American planters Category:British North American Anglicans Category:American people of English descent Category:Mason family Category:People from Fairfax County, Virginia Category:People from Stafford County, Virginia Category:People of Virginia in the American Revolution Category:Virginia politicians Category:Virginia lawyers Category:Virginia colonial people

Playername	Arthur Ashe
Caption	Arthur Ashe greets President Reagan in 1982
Country	United States
Residence	Petersburg, Virginia
Datebirth	July 10, 1943|placebirth = Richmond, Virginia, USA
Datedeath	February 06, 1993
Placedeath	New York City, New York, USA
Height
Weight
Turnedpro	1969
Retired	1980
Plays	Right-handed (one-handed backhand)
Careerprizemoney	US$1,584,909 (according to the ATP)
Tennishofyear	1985
Tennishofid	arthur-ashe
Singlesrecord	818-260 (at Grand Prix tour, WCT tour, and Grand Slam level, and in Davis Cup)
Singlestitles	33
Highestsinglesranking	No. 1 (1969)
Australianopenresult	W (1970)
Frenchopenresult	QF (1970, 1971)
Wimbledonresult	W (1975)
Usopenresult	W (1968)
Doublesrecord	323-176 (at Grand Prix tour, WCT tour, and Grand Slam level, and in Davis Cup)
Doublestitles	18 (14 according to the ATP)
Highestdoublesranking	15 (30 August, 1977)
Grandslamsdoublesresults	yes
Australianopendoublesresult	W (1977)
Frenchopendoublesresult	W (1971)
Wimbledondoublesresult	F (1971)
Usopendoublesresult	F (1968)

Arthur Robert Ashe, Jr. (July 10, 1943 – February 6, 1993) was a professional tennis player, born and raised in Richmond, Virginia. During his career, he won three Grand Slam titles, putting him among the best ever from the U.S. Ashe, an African American, is also remembered for his efforts to further social causes.

Early life and tennis career

Arthur Ashe first attended Maggie L. Walker High School, being coached by Ronald Charity, and later coached by Robert Walter Johnson. Tired of having to travel great distances to play Caucasian youths in segregated Richmond, Ashe accepted an offer from a St. Louis tennis official to move there and attend Sumner High School. A = did not participate in the tournament SR = the ratio of the number of Grand Slam singles tournaments won to the number of those tournaments played

Activities after retirement from professional tennis

After his retirement, Ashe took on many new tasks, including writing for Time magazine, commentating for ABC Sports, founding the National Junior Tennis League, and serving as captain of the U.S. Davis Cup team. In 1983, Ashe underwent a second heart surgery. He was elected to the International Tennis Hall of Fame in 1985. He also founded the Arthur Ashe Foundation for the Defeat of AIDS.

In 1983, Ashe underwent a second round of heart surgery to correct the bypass surgery he received back in 1979. In 1988, Ashe fell ill and discovered he had apparently contracted HIV during the blood transfusions he had received during his second heart surgery. He and his wife kept his illness private until April 8, 1992, when reports that the newspaper USA Today was about to publish a story about his health condition because of his increasingly gaunt physical appearance forced him to make a public announcement that he had the disease. In the last year of his life, Ashe did much to call attention to AIDS sufferers worldwide. Two months before his death, he founded the Arthur Ashe Institute for Urban Health to help address issues of inadequate health care delivery and was named Sports Illustrated magazine's Sportsman of the Year. He also spent much of the last years of his life writing his memoir Days of Grace, finishing the manuscript less than a week before his death.

Ashe died from AIDS-related pneumonia on February 6, 1993.

Civil rights leader

Ashe, the first African-American male to win a Grand Slam event, was an active civil rights supporter. He was a member of a delegation of 31 prominent African-Americans who visited South Africa to observe political change in the country as it approached racial integration.

He was arrested on January 11, 1985, for protesting outside the South African embassy in Washington, D.C. during an anti-apartheid rally. He was also arrested again on September 9, 1992, outside the White House for protesting on the recent crackdown on Haitian refugees.

Honors

at the 2007 US Open]]

In 1985 Ashe was inducted into the International Tennis Hall of Fame.

After his death, Arthur Ashe's body lay in state at the governor's mansion in his home state of Virginia. The last time this was allowed was for Stonewall Jackson of the Confederate Army during the Civil War.

The city of Richmond posthumously honored Ashe's life with a statue on Monument Avenue, a place traditionally reserved for statues of key figures of the Confederacy. This decision led to some controversy in a city that was the capital of the Confederate States during the American Civil War.

In 1993, Ashe was posthumously awarded the Presidential Medal of Freedom by President Bill Clinton.

The main stadium at the USTA National Tennis Center in Flushing Meadows Park, where the US Open is played, is named Arthur Ashe Stadium in his honor. This is also the home of the annual Arthur Ashe Kids' Day.

In 2002, Ashe's achievement at Wimbledon in 1975 was voted 95th in Channel 4's 100 Greatest Sporting Moments.

In 2002, scholar Molefi Kete Asante listed Arthur Ashe on his list of 100 Greatest African Americans.

In 2005, the United States Postal Service announced the release of an Arthur Ashe commemorative postal stamp, the first stamp ever to feature the cover of a Sports Illustrated magazine.

Also in 2005, TENNIS Magazine put him in 30th place in their list of the 40 Greatest Players of the TENNIS Era.

His wife wrote a book, Daddy and Me, a photographic journey told from the perspective of his young daughter. Another book, Arthur Ashe and Me, also gives young readers a chance to learn about his life.

ESPN's annual sports awards, the ESPY Awards, hands out the Arthur Ashe for Courage Award to a member of the sports world who best exhibits courage in the face of adversity.

Philadelphia's Arthur Ashe Youth Tennis and Education Center and Richmond's Arthur Ashe Athletic Center are named for Ashe.

The Arthur Ashe Student Health and Wellness Center at Ashe's alma mater, UCLA, is named for him. The center opened in 1997.

He was inducted into the Intercollegiate Tennis Association (ITA) Hall of Fame in 1983.

Schools

There are a number of schools honoring Arthur Ashe. In Henrico County, Virginia (adjacent to Richmond), an elementary school in his honor was opened in the fall of 1994 as Henrico County's first volunteer uniform school, with grades kindergarten through five, a PEDD program, and a Head Start program. The Arthur Ashe Charter school in New Orleans, Louisiana. P.S. 161 - Arthur Ashe school within New York School district #28 is located in Jamacia, NY. The Arthur Robert Ashe, Jr Middle School in Fort Lauderdale, Florida. The Arthur Ashe Academy in Michigan is part of the Southfield School district offering sixth through eleventh grades.

Grand Slam finals

Singles: 7 finals (3 titles, 4 runner-ups)

{| class="sortable wikitable" |width="100"|Outcome |width="50"|Year |width="200"|Championship |width="75"|Surface |width="200"|Opponent in the final |width="200"|Score in the final |-bgcolor="#FFFFCC" | bgcolor="FFA07A"|Runner-up || 1966 || Australian Championships || Grass || Roy Emerson || 6–4, 6–8, 6–2, 6–3 |-bgcolor="#FFFFCC" | bgcolor="FFA07A"|Runner-up || 1967 || Australian Championships || Grass || Roy Emerson || 6–4, 6–1, 6–4 |-bgcolor="#CCCCFF" | bgcolor="98FB98"|Winner ||1968 || US Open || Grass || Tom Okker || 14–12, 5–7, 6–3, 3–6, 6–3 |-bgcolor="#FFFFCC" | bgcolor="98FB98"|Winner ||1970 || Australian Open || Grass || Dick Crealy || 6–4, 9–7, 6–2 |-bgcolor="#FFFFCC" | bgcolor="FFA07A"|Runner-up || 1971 || Australian Open || Grass || Ken Rosewall || 6–1, 7–5, 6–3 |-bgcolor="#CCCCFF" | bgcolor="FFA07A"|Runner-up || 1972 || US Open || Grass || Ilie Năstase || 3–6, 6–3, 6–7(1–5), 6–4, 6–3 |-bgcolor="#CCFFCC" | bgcolor="98FB98"|Winner ||1975 || Wimbledon || Grass || Jimmy Connors || 6–1, 6–1, 5–7, 6–4 |}

Grand Slam, Grand Prix and WCT Tour titles (33)

Singles

1972 – Louisville WCT, Montreal WCT, Rome WCT, Rotterdam WCT

1973 – Chicago WCT, Washington

1974 – Barcelona WCT, Bologna WCT, Stockholm

1975 – Barcelona WCT, WCT Finals, Los Angeles, Munich WCT, Rotterdam WCT, San Francisco, Stockholm - WCT, Wimbledon

1976 – Columbus WCT, Indianapolis WCT, Richmond WCT, Rome WCT, Rotterdam WCT

1978 – Colombus, Los Angeles, San Jose

Quotations

"Success is a journey, not a destination." "True heroism is remarkably sober, very undramatic. It is not the urge to surpass all at whatever cost, but the urge to serve others at whatever cost." "You are never really playing an opponent. You are playing yourself, your own highest standards, and when you reach your limits, that is real joy." "If one's reputation is a possession, then of all my possessions, my reputation means most to me."

"I respected the way they stood tall against the sky and insisted on being heard in matters other than Track and Field -- on matters of Civil Rights and social responsibility. I couldn't help but admire them." --- on the Olympic athletes Tommie Smith and John Carlos when they did the Black Power Salute at the 1968 Olympics in Mexico City (as quoted by Samuel L. Jackson at the 2008 Espys)

"From what we get, we make a living; what we give, however, makes a life." (paraphrasing Winston Churchill -"You make a living by what you get; you make a life by what you give") "I believe I was destined to do more than hit tennis balls" “If I were to say, God, why me? about the bad things, then I should have said, God, why me? about the good things that happened in my life.” When he received a letter from a fan which conveyed:”Why did God have to select you for such a bad disease?” Ashe replied: "Listen. 50 million children around the world start playing tennis. 5 million learn to play tennis. 500,000 learn professional tennis. 50,000 come to the circuit. 5000 reach The Grand Slam. 50 reach Wimbledon. 8 reach the Quarterfinals. 4 to the Semifinals. 2 to the Finals. When i was holding the Cup i never asked God: Why me? So why now in pain should I be asking Him: WHY ME?

Video

Wimbledon 1975 Final: Ashe vs. Connors Standing Room Only, DVD Release Date: October 30, 2007, Run Time: 120 minutes, ASIN: B000V02CTQ.

See also

Arthur Ashe Stadium, New York, NY

Arthur Ashe Athletic Center, Richmond, VA

Arthur Ashe Courage Award

Arthur Ashe Kids' Day

Levels of the Game, a 1969 book by John McPhee, exploring the 1968 U.S. Open semifinal match between Clark Graebner and Arthur Ashe

Further reading

Books by Arthur Ashe.

Books about Arthur Ashe, by date published.

References

External links

Arthur Ashe Learning Center (AALC) Website

Sign Up for Arthur Ashe Learning Center (AALC) Newsletter

Official Arthur Ashe website

International Tennis Hall of Fame

Sports Illustrated Arthur Ashe tribute website

Arthur Ashe Institute for Urban Health

FBI files—Arthur Ashe is mentioned within six references of records maintained within FBIHQ main files concerning the Black Panther Party, the Student Non-Violent Coordinating Committee, the Revolutionary Union and two newspaper articles.

The Game — My 40 Years in Tennis (1979) — Jack Kramer with Frank Deford (ISBN 0-399-12336-9)

Arthur Ashe Youth Tennis and Education Manayunk, PA

The New York Times, February 8, 1993.">Finn, Robin. "Arthur Ashe, Tennis Star, Is Dead at 49," The New York Times, February 8, 1993.

UCLA Arthur Ashe Student Health & Wellness Center

Category:African American sports journalists Category:African American tennis players Category:AIDS-related deaths in New York Category:American color commentators Category:American male tennis players Category:Australian Open (tennis) champions Category:French Open champions Category:People from Petersburg, Virginia Category:People from Richmond, Virginia Category:People from St. Louis, Missouri Category:Presidential Medal of Freedom recipients Category:Sportspeople from New York City Category:Tennis commentators Category:International Tennis Hall of Fame inductees Category:Tennis people from Missouri Category:Tennis people from New York Category:Tennis people from Virginia Category:UCLA Bruins tennis players Category:United States Open champions (tennis) Category:Wimbledon champions Category:1943 births Category:1993 deaths

Name	Sir Mix-a-Lot
Background	solo_singer
Birth name	Anthony Ray
Born	August 12, 1963
Origin	Seattle, Washington, U.S.
Genre	Hip hop
Occupation	Rapper, record producer, songwriter
Years active	1985–present
Label	Nastymix/Ichiban Records, American Recordings/Warner Bros. Records, Artist Direct/BMG Records
Url	www.sirmixalot.com

Anthony Ray (born August 12, 1963), better known by his stage name Sir Mix-a-Lot, is an emcee and producer based in Seattle, Washington. The founder of the Nastymix record label, he debuted in 1988 with Swass. In 1992, he debuted on a major label with his album Mack Daddy, whose single "Baby Got Back" reached the top of the American singles chart and won a Grammy Award.

Career

In 1986, Sir Mix-a-Lot and his DJ, Nasty Nes founded the Nastymix record label. His first hit, released in 1987, was the single "Posse on Broadway," whose title referred to a street in Seattle's Capitol Hill district. In 1990, the Recording Industry Association of America (RIAA) certified Swass platinum for selling a million copies. and won the 1993 Grammy Award for Best Rap Solo Performance.

Low label promotion of his 1996 album Return of the Bumpasaurus led Sir Mix-a-Lot to leave the American label. During the three year break, Sir Mix-a-Lot worked closely with another group, The Presidents of the United States of America under the group name "Subset" with a combination of rock and rap music, but nothing was ever officially released. Sir Mix-a-Lot signed with the independent Artist Direct label for his 2003 album Daddy's Home with "Big Johnson" as its lead single. Despite having taken several years off from recording, Sir Mix-a-Lot is still known to mix frequently.

Film and Television

In 1995, Sir Mix-a-Lot starred as the titular character of the short-lived TV series The Watcher. The show was one of the first dramas aired on the fledgling broadcast network, UPN. Reminiscent of series such as The Twilight Zone, Sir-Mix-a-Lot functioned as an omniscient narrator who introduced each episode, which would feature a new tale set in the seamy underbelly of Las Vegas. In Las Vegas he fought UFOs.

In 2006, Sir Mix-a-Lot appeared as himself in the second season episode of Tom Goes to the Mayor, , in which he raps the jingle for Tom's latest commercial enterprise, a store that sells big cups. He is currently trying to make a comeback with a new label that should make its release at the end of 2011.

Sir Mix-a-Lot provides narration and commentary in Wheedle's Groove, a 2009 documentary about the Seattle '60s/'70s funk and soul scene.

Discography

Albums

Singles

Videos

"Posse on Broadway"

"Iron Man"

"My Hooptie"

"Beepers"

"Baby Got Back"

"Ride"

"One Time's Got No Case"

""

"Put 'Em on the Glass"

"Batter Up"

"Carz"

VHS

Maconomics

DVDs

Shhh... Don't Tell 'em That

References

External links

Sir Mix-A-Lot Official site

Official site at Artist Direct

Sir Mix-A-Lot at MySpace

Subset

Category:1963 births Category:Living people Category:African American rappers Category:People from Seattle, Washington Category:Grammy Award winners Category:rappers from Washington (U.S. state)

Name	Alison Gertz
Birth name	Alison L. Gertz
Birth date	February 27, 1966
Birth place	Manhattan, New York
Death date	August 08, 1992
Death place	Manhattan, New York

Alison Gertz (February 27, 1966 – August 8, 1992) was a prominent AIDS activist in the late 1980s and early 1990s, who died from AIDS related complications in 1992.

Biography

Gertz was first diagnosed with AIDS in 1988 and later found out that she had contracted HIV from her first sexual encounter in 1982. She became an AIDS activist, appearing on numerous television shows and also speaking with teenagers on the subject of safe sex.

During Gertz' time as an activist, she was voted Woman of the Year by Esquire magazine, received the Secretary's Award for Excellence in Public Service from the United States Department of Health and Human Services, and a based on her life starring Molly Ringwald was released.

Gertz died of complications arising from AIDS on August 8, 1992. She was 26 years old.

Alison Gertz was referred to in the song "Life Support" from the rock opera RENT. At the beginning of the song, various members of the group say their names. Jonathan Larson used the names of his HIV-positive friends as the characters in this song. At the beginning of the song, the character who refers to herself as "Ali" was named after Gertz.

References

External links

Love Heals - The Alison Gertz Foundation for AIDS education

Obituary in the New York Times

Category:1966 births Category:1992 deaths Category:AIDS activists Category:AIDS-related deaths in New York Category:Horace Mann School alumni Category:People from Manhattan Category:American health activists