The Khojas (Urdu: خوجہ) are a set of communities of Shia Muslims in the Indian Subcontinent. The word Khoja derives from Khwaja, a Persian/Turkic honorific title (Persian: خواجه‎) that is widespread across Muslim societies and cultures with different spelling.

In Pakistan, many Khojas migrated to and settled in the province of Sindh and especially in the city of Karachi. While in India, most Khojas live in the states of Gujarat, Maharashtra, Rajasthan and the city of Hyderabad. Many Khojas have also migrated and settled over the centuries in East Africa, Europe and North America. The Khoja were originally adherents of Ismaili Shi'a Islam. In the late 19th and early 20th century, a minority separated and adopted Twelver Shi'ism or Sunni Islam, while the majority remained Ismaili.

The term Khwaja, pronounced Khoja in the Gujarati language, is a Persian honorific title, first bestowed by the Ismaili Pir Sadardin (d. c. 15th c) upon his followers during the lifetime of the Imam Islam Shah (1368-1423 CE). As such, Pir Shihab al-din Shah wrote regarding the origins of the Khojas that the very formation of the community came about through Pir Sadardin’s devotion to the Imam.